SESN3 Antikörper (AA 1-310)
Kurzübersicht für SESN3 Antikörper (AA 1-310) (ABIN6147627)
Target
Alle SESN3 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 1-310
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Sequenz
- MNRGGGSPSA AANYLLCTNC RKVLRKDKRI RVSQPLTRGP SAFIPEKEVV QANTVDERTN FLVEEYSTSG RLDNITQVMS LHTQYLESFL RSQFYMLRMD GPLPLPYRHY IAIMAAARHQ CSYLINMHVD EFLKTGGIAE WLNGLEYVPQ RLKNLNEINK LLAHRPWLIT KEHIQKLVKT GENNWSLPEL VHAVVLLAHY HALASFVFGS GINPERDPEI SNGFRLISVN NFCVCDLAND NNIENASLSG SNFGIVDSLS ELEALMERMK RLQEEREDEE ASQEEMSTRF EKEKKESLFV VSGDTFHSFP
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Kreuzreaktivität
- Human
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Produktmerkmale
- Polyclonal Antibodies
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Immunogen
- Recombinant fusion protein containing a sequence corresponding to amino acids 1-310 of human SESN3 (NP_653266.2).
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Isotyp
- IgG
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Applikationshinweise
- WB,1:200 - 1:2000
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Kommentare
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HIGH QUALITY
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Store at -20°C. Avoid freeze / thaw cycles.
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- SESN3 (Sestrin 3 (SESN3))
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Andere Bezeichnung
- SESN3
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Hintergrund
- This gene encodes a member of the sestrin family of stress-induced proteins. The encoded protein reduces the levels of intracellular reactive oxygen species induced by activated Ras downstream of RAC-alpha serine/threonine-protein kinase (Akt) and FoxO transcription factor. The protein is required for normal regulation of blood glucose, insulin resistance and plays a role in lipid storage in obesity. Alternative splicing results in multiple transcript variants.,SESN3,SEST3,sestrin-3,Cancer,Tumor suppressors,Cell Biology & Developmental Biology,Endocrine & Metabolism,AMPK Signaling Pathway,Endocrine and metabolic diseases,Diabetes,Cardiovascular,Hypoxia,Hypoxia-Regulated,SESN3
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Molekulargewicht
- 36 kDa/41 kDa/57 kDa
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Gen-ID
- 143686
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UniProt
- P58005
Target
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