S100A12 Antikörper (AA 1-92)

Produktnummer ABIN6147336

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch S100A12 in WB, IHC und IF. Er zeigt eine Reaktivität gegenüber Human und wurde in 1 Publikation erwähnt.

Kurzübersicht für S100A12 Antikörper (AA 1-92) (ABIN6147336)

Target: S100A12 (S100 Calcium Binding Protein A12 (S100A12))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser S100A12 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Produktdetails anti-S100A12 Antikörper

Bindungsspezifität: AA 1-92

Sequenz: MTKLEEHLEG IVNIFHQYSV RKGHFDTLSK GELKQLLTKE LANTIKNIKD KAVIDEIFQG LDANQDEQVD FQEFISLVAI ALKAAHYHTH KE

Kreuzreaktivität: Human, Maus, Ratte

Produktmerkmale: Polyclonal Antibodies

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-92 of human S100A12 (NP_005612.1).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB,1:500 - 1:2000,IHC,1:50 - 1:200,IF,1:50 - 1:200

Kommentare:

HIGH QUALITY

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Referenzen für anti-S100A12 Antikörper (ABIN6147336)

Yao, Zhao, Tang, Liang, Liu, Dong, Zou, Cai: "The receptor for advanced glycation end products is required for β-catenin stabilization in a chemical-induced asthma model." in: British journal of pharmacology, Vol. 173, Issue 17, pp. 2600-13, (2017) (PubMed).

Details zu S100A12

Target: S100A12 (S100 Calcium Binding Protein A12 (S100A12))

Andere Bezeichnung: S100A12

Hintergrund: The protein encoded by this gene is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21. This protein is proposed to be involved in specific calcium-dependent signal transduction pathways and its regulatory effect on cytoskeletal components may modulate various neutrophil activities. The protein includes an antimicrobial peptide which has antibacterial activity.,S100A12,CAAF1,CAGC,CGRP,ENRAGE,MRP-6,MRP6,p6,Signal Transduction,Immunology & Inflammation,Cytokines,Cell Intrinsic Innate Immunity Signaling Pathway,Neuroscience,Calcium Signaling,S100A12

Molekulargewicht: 10 kDa

Gen-ID: 6283

UniProt: P80511

Pathways: Toll-Like Receptors Cascades, S100 Proteine