RTN4RL1 Antikörper (AA 220-420)
Kurzübersicht für RTN4RL1 Antikörper (AA 220-420) (ABIN6147298)
Target
Alle RTN4RL1 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 220-420
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Sequenz
- LRRLTTLFLF NNSLSELQGE CLAPLGALEF LRLNGNPWDC GCRARSLWEW LQRFRGSSSA VPCVSPGLRH GQDLKLLRAE DFRNCTGPAS PHQIKSHTLT TTDRAARKEH HSPHGPTRSK GHPHGPRPGH RKPGKNCTNP RNRNQISKAG AGKQAPELPD YAPDYQHKFS FDIMPTARPK RKGKCARRTP IRAPSGVQQA S
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Kreuzreaktivität
- Maus, Ratte
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Produktmerkmale
- Polyclonal Antibodies
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Immunogen
- Recombinant fusion protein containing a sequence corresponding to amino acids 220-420 of human RTN4RL1 (NP_848663.1).
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Isotyp
- IgG
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Applikationshinweise
- WB,1:1000 - 1:4000
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Kommentare
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HIGH QUALITY
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Store at -20°C. Avoid freeze / thaw cycles.
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- RTN4RL1 (Reticulon 4 Receptor-Like 1 (RTN4RL1))
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Andere Bezeichnung
- RTN4RL1
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Hintergrund
- Cell surface receptor. Plays a functionally redundant role in postnatal brain development and in regulating axon regeneration in the adult central nervous system. Contributes to normal axon migration across the brain midline and normal formation of the corpus callosum. Protects motoneurons against apoptosis, protection against apoptosis is probably mediated by MAG. Plays a role in inhibiting neurite outgrowth and axon regeneration via its binding to neuronal chondroitin sulfate proteoglycans. Binds heparin (By similarity. Like other family members, plays a role in restricting the number dendritic spines and the number of synapses that are formed during brain development. Signaling mediates activation of Rho and downstream reorganization of the actin cytoskeleton.,RTN4RL1,NGRH2,NgR3,Neuroscience,RTN4RL1
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Molekulargewicht
- 49 kDa
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Gen-ID
- 146760
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UniProt
- Q86UN2
Target
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