RORA Antikörper (AA 169-468)

Produktnummer ABIN6147077

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch RORA in WB. Er zeigt eine Reaktivität gegenüber Human.

Kurzübersicht für RORA Antikörper (AA 169-468) (ABIN6147077)

Target: RORA (RAR-Related Orphan Receptor A (RORA))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser RORA Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-RORA Antikörper

Bindungsspezifität: AA 169-468

Sequenz: DIQPSPDQSG LDINGIKPEP ICDYTPASGF FPYCSFTNGE TSPTVSMAEL EHLAQNISKS HLETCQYLRE ELQQITWQTF LQEEIENYQN KQREVMWQLC AIKITEAIQY VVEFAKRIDG FMELCQNDQI VLLKAGSLEV VFIRMCRAFD SQNNTVYFDG KYASPDVFKS LGCEDFISFV FEFGKSLCSM HLTEDEIALF SAFVLMSADR SWLQEKVKIE KLQQKIQLAL QHVLQKNHRE DGILTKLICK VSTLRALCGR HTEKLMAFKA IYPDIVRLHF PPLYKELFTS EFEPAMQIDG

Kreuzreaktivität: Human, Maus, Ratte

Produktmerkmale: Polyclonal Antibodies

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 169-468 of human RORA (NP_599024.1).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB,1:500 - 1:2000

Kommentare:

HIGH QUALITY

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu RORA

Target: RORA (RAR-Related Orphan Receptor A (RORA))

Andere Bezeichnung: RORA

Hintergrund: The protein encoded by this gene is a member of the NR1 subfamily of nuclear hormone receptors. It can bind as a monomer or as a homodimer to hormone response elements upstream of several genes to enhance the expression of those genes. The encoded protein has been shown to interact with NM23-2, a nucleoside diphosphate kinase involved in organogenesis and differentiation, as well as with NM23-1, the product of a tumor metastasis suppressor candidate gene. Also, it has been shown to aid in the transcriptional regulation of some genes involved in circadian rhythm. Four transcript variants encoding different isoforms have been described for this gene.,RORA,NR1F1,ROR1,ROR2,ROR3,RZR-ALPHA,RZRA,Epigenetics & Nuclear Signaling,Transcription Factors,Nuclear Receptor Signaling,Nuclear hormone receptors,Cancer,Signal Transduction,Cell Biology & Developmental Biology,Cell Cycle,Cell differentiation,Neuroscience,RORA

Molekulargewicht: 53 kDa/58 kDa/61 kDa/63 kDa

Gen-ID: 6095

UniProt: P35398

Pathways: Nuclear Receptor Transcription Pathway, Steroid Hormone Mediated Signaling Pathway, Regulation of Lipid Metabolism by PPARalpha