RNF166 Antikörper (C-Term)
Kurzübersicht für RNF166 Antikörper (C-Term) (ABIN6147021)
Target
Alle RNF166 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- C-Term
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Sequenz
- GCNKKVTLAK MRVHISSCLK VQEQMANCPK FVPVVPTSQP IPSNIPNRST FACPYCGARN LDQQELVKHC VESHRSDPNR VVCPICSAMP WGDPSYKSAN FLQHLLHRHK FSYDTFVDYS IDEEAAFQAA LALSLSEN
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Kreuzreaktivität
- Human, Maus, Ratte
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Produktmerkmale
- Polyclonal Antibodies
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Immunogen
- A synthetic peptide corresponding to a sequence within amino acids 100 to the C-terminus of human RNF166 (NP_849163.1).
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Isotyp
- IgG
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Applikationshinweise
- WB,1:500 - 1:2000,IHC,1:50 - 1:200
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Store at -20°C. Avoid freeze / thaw cycles.
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: "Identification of genes associated with cortical malformation using a transposon-mediated somatic mutagenesis screen in mice." in: Nature communications, Vol. 9, Issue 1, pp. 2498, (2019) (PubMed).
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: "Identification of genes associated with cortical malformation using a transposon-mediated somatic mutagenesis screen in mice." in: Nature communications, Vol. 9, Issue 1, pp. 2498, (2019) (PubMed).
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- RNF166 (Ring Finger Protein 166 (RNF166))
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Andere Bezeichnung
- RNF166
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Hintergrund
- E3 ubiquitin-protein ligase that promotes the ubiquitination of different substrates. In turn, participates in different biological processes including interferon production or autophagy. Plays a role in the activation of RNA virus-induced interferon-beta production by promoting the ubiquitination of TRAF3 and TRAF6. Plays also a role in the early recruitment of autophagy adapters to bacteria. Mediates 'Lys-29' and 'Lys-33'-linked ubiquitination of SQSTM1 leading to xenophagic targeting of bacteria and inhibition of their replication.,RNF166,Cell Biology & Developmental Biology,Ubiquitin,RNF166
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Molekulargewicht
- 14 kDa/17 kDa/26 kDa
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Gen-ID
- 115992
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UniProt
- Q96A37
Target
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