Ribonuclease H1 Antikörper (AA 1-286)

Produktnummer ABIN6146988

Dieses Anti-Ribonuclease H1-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von Ribonuclease H1 in WB und IHC. Geeignet für Human.

Kurzübersicht für Ribonuclease H1 Antikörper (AA 1-286) (ABIN6146988)

Target: Ribonuclease H1 (RNASEH1)

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Ribonuclease H1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Produktdetails anti-Ribonuclease H1 Antikörper

Bindungsspezifität: AA 1-286

Sequenz: MSWLLFLAHR VALAALPCRR GSRGFGMFYA VRRGRKTGVF LTWNECRAQV DRFPAARFKK FATEDEAWAF VRKSASPEVS EGHENQHGQE SEAKASKRLR EPLDGDGHES AEPYAKHMKP SVEPAPPVSR DTFSYMGDFV VVYTDGCCSS NGRRRPRAGI GVYWGPGHPL NVGIRLPGRQ TNQRAEIHAA CKAIEQAKTQ NINKLVLYTD SMFTINGITN WVQGWKKNGW KTSAGKEVIN KEDFVALERL TQGMDIQWMH VPGHSGFIGN EEADRLAREG AKQSED

Kreuzreaktivität: Human, Maus, Ratte

Produktmerkmale: Polyclonal Antibodies

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-286 of human RNASEH1 (NP_002927.2).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB,1:500 - 1:2000,IHC,1:100 - 1:200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu Ribonuclease H1

Target: Ribonuclease H1 (RNASEH1)

Andere Bezeichnung: RNASEH1

Hintergrund: This gene encodes an endonuclease that specifically degrades the RNA of RNA-DNA hybrids and is necessary for DNA replication and repair. This enzyme is present in both mitochondria and nuclei, which are resulted from translation of a single mRNA with two in-frame initiation start codons. The use of the first start codon produces the mitochondrial isoform and the use of the second start codon produces the nuclear isoform. The production of the mitochondrial isoform is modulated by an upstream open reading frame (uORF) which overlaps the first initiation start codon in human. An alternately spliced transcript variant has been found which encodes a shorter isoform. This gene has three pseudogenes, two of them are at different locations of chromosome 17 and one of them is on chromosome 1q32.2.,RNASEH1,H1RNA,PEOB2,RNH1,Epigenetics & Nuclear Signaling,RNASEH1

Molekulargewicht: 32 kDa

Gen-ID: 246243

UniProt: O60930