RASGRP1 Antikörper (AA 598-797)

Produktnummer ABIN6146720

Dieses Anti-RASGRP1-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von RASGRP1 in WB und IF. Geeignet für Human.

Kurzübersicht für RASGRP1 Antikörper (AA 598-797) (ABIN6146720)

Target: RASGRP1 (RAS Guanyl Releasing Protein 1 (Calcium and DAG-Regulated) (RASGRP1))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser RASGRP1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (IF)

Produktdetails anti-RASGRP1 Antikörper

Bindungsspezifität: AA 598-797

Sequenz: PVAPTENNTS VGPVSNLCSL GAKDLLHAPE EGPFTFPNGE AVEHGEESKD RTIMLMGVSS QKISLRLKRA VAHKATQTES QPWIGSEGPS GPFVLSSPRK TAQDTLYVLP SPTSPCPSPV LVRKRAFVKW ENKDSLIKSK EELRHLRLPT YQELEQEINT LKADNDALKI QLKYAQKKIE SLQLEKSNHV LAQMEQGDCS

Kreuzreaktivität: Human, Maus, Ratte

Produktmerkmale: Polyclonal Antibodies

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 598-797 of human RASGRP1 (NP_005730.2).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB,1:1000 - 1:2000,IF,1:50 - 1:200

Kommentare:

HIGH QUALITY

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu RASGRP1

Target: RASGRP1 (RAS Guanyl Releasing Protein 1 (Calcium and DAG-Regulated) (RASGRP1))

Andere Bezeichnung: RASGRP1

Hintergrund: This gene is a member of a family of genes characterized by the presence of a Ras superfamily guanine nucleotide exchange factor (GEF) domain. It functions as a diacylglycerol (DAG)-regulated nucleotide exchange factor specifically activating Ras through the exchange of bound GDP for GTP. It activates the Erk/MAP kinase cascade and regulates T-cells and B-cells development, homeostasis and differentiation. Alternatively spliced transcript variants encoding different isoforms have been identified. Altered expression of the different isoforms of this protein may be a cause of susceptibility to systemic lupus erythematosus (SLE).,RASGRP1,CALDAG-GEFI,CALDAG-GEFII,RASGRP,V,hRasGRP1,Cancer,Signal Transduction,G protein signaling,Signal Transduction,Immunology & Inflammation,B Cell Receptor Signaling Pathway,T Cell Receptor Signaling Pathway,Neuroscience,Calcium Signaling,RASGRP1

Molekulargewicht: 55 kDa/62 kDa/68 kDa/86 kDa/90 kDa

Gen-ID: 10125

UniProt: O95267

Pathways: T-Zell Rezeptor Signalweg, Fc-epsilon Rezeptor Signalübertragung