PTPMT1 Antikörper (AA 1-201)

Produktnummer ABIN6146436

Dieses Anti-PTPMT1-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von PTPMT1 in WB. Geeignet für Human.

Kurzübersicht für PTPMT1 Antikörper (AA 1-201) (ABIN6146436)

Target: PTPMT1 (Protein Tyrosine Phosphatase, Mitochondrial 1 (PTPMT1))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PTPMT1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-PTPMT1 Antikörper

Bindungsspezifität: AA 1-201

Sequenz: MAATALLEAG LARVLFYPTL LYTLFRGKVP GRAHRDWYHR IDPTVLLGAL PLRSLTRQLV QDENVRGVIT MNEEYETRFL CNSSQEWKRL GVEQLRLSTV DMTGIPTLDN LQKGVQFALK YQSLGQCVYV HCKAGRSRSA TMVAAYLIQV HKWSPEEAVR AIAKIRSYIH IRPGQLDVLK EFHKQITARA TKDGTFVISK T

Kreuzreaktivität: Maus

Produktmerkmale: Polyclonal Antibodies

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-201 of human PTPMT1 (NP_783859.1).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB,1:500 - 1:2000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu PTPMT1

Target: PTPMT1 (Protein Tyrosine Phosphatase, Mitochondrial 1 (PTPMT1))

Andere Bezeichnung: PTPMT1

Hintergrund: Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP to phosphatidylglycerol (PG (By similarity. PGP is an essential intermediate in the biosynthetic pathway of cardiolipin, a mitochondrial-specific phospholipid regulating the membrane integrity and activities of the organelle (By similarity. Has also been shown to display phosphatase activity toward phosphoprotein substrates, specifically mediates dephosphorylation of mitochondrial proteins, thereby playing an essential role in ATP production (By similarity. Has probably a preference for proteins phosphorylated on Ser and/or Thr residues compared to proteins phosphorylated on Tyr residues (By similarity. Probably involved in regulation of insulin secretion in pancreatic beta cells (By similarity. May prevent intrinsic apoptosis, probably by regulating mitochondrial membrane integrity.,PTPMT1,DUSP23,MOSP,PLIP,PNAS-129,Signal Transduction,PTPMT1

Molekulargewicht: 15 kDa/16 kDa/22 kDa

Gen-ID: 114971

UniProt: Q8WUK0

Pathways: Inositol Metabolic Process