Der Maus Monoklonal anti-Hemoglobin Subunit beta Antikörper (Klon 7B12) (ABIN614613) detektiert spezifisch Hemoglobin Subunit beta in WB, IHC (p) und EIA.
Dieser Antikörper reagiert spezifisch mit Proben aus Human.
The alpha (HBA) and beta (HBB) loci determine the structure of the 2 types of polypeptide chains in adult hemoglobin, Hb A. The normal adult hemoglobin tetramer consists of two alpha chains and two beta chains. Mutant beta globin that sickles causes sickle cell anemia. Absence of beta chain causes beta-zero-thalassemia. Reduced amounts of detectable beta globin causes beta-plus-thalassemia. The order of the genes in the beta-globin cluster is 5'-epsilon -- gamma-G -- gamma-A -- delta -- beta--3'.Synonyms: Beta-globin, HBB