POLG Antikörper (AA 980-1239)
Kurzübersicht für POLG Antikörper (AA 980-1239) (ABIN6145892)
Target
Alle POLG Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 980-1239
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Sequenz
- EKAQQMYAAT KGLRWYRLSD EGEWLVRELN LPVDRTEGGW ISLQDLRKVQ RETARKSQWK KWEVVAERAW KGGTESEMFN KLESIATSDI PRTPVLGCCI SRALEPSAVQ EEFMTSRVNW VVQSSAVDYL HLMLVAMKWL FEEFAIDGRF CISIHDEVRY LVREEDRYRA ALALQITNLL TRCMFAYKLG LNDLPQSVAF FSAVDIDRCL RKEVTMDCKT PSNPTGMERR YGIPQGEALD IYQIIELTKG SLEKRSQPGP
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Kreuzreaktivität
- Human
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Produktmerkmale
- Polyclonal Antibodies
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Immunogen
- Recombinant fusion protein containing a sequence corresponding to amino acids 980-1239 of human DNA Polymerase gamma (NP_002684.1).
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Isotyp
- IgG
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Applikationshinweise
- WB,1:500 - 1:2000
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Store at -20°C. Avoid freeze / thaw cycles.
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- POLG (Polymerase (DNA Directed), gamma (POLG))
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Andere Bezeichnung
- POLG
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Substanzklasse
- Viral Protein
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Hintergrund
- Mitochondrial DNA polymerase is heterotrimeric, consisting of a homodimer of accessory subunits plus a catalytic subunit. The protein encoded by this gene is the catalytic subunit of mitochondrial DNA polymerase. The encoded protein contains a polyglutamine tract near its N-terminus that may be polymorphic. Defects in this gene are a cause of progressive external ophthalmoplegia with mitochondrial DNA deletions 1 (PEOA1), sensory ataxic neuropathy dysarthria and ophthalmoparesis (SANDO), Alpers-Huttenlocher syndrome (AHS), and mitochondrial neurogastrointestinal encephalopathy syndrome (MNGIE). Two transcript variants encoding the same protein have been found for this gene.,POLG,MDP1,MIRAS,MTDPS4A,MTDPS4B,PEO,POLG1,POLGA,SANDO,SCAE,Epigenetics & Nuclear Signaling,Endocrine & Metabolism,Mitochondrial metabolism,Mitochondrial Biogenesis,Nucleotide metabolism,Molecular processes,POLG
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Molekulargewicht
- 139 kDa
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Gen-ID
- 5428
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UniProt
- P54098
Target
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