PLOD1 Antikörper (AA 488-727)
Kurzübersicht für PLOD1 Antikörper (AA 488-727) (ABIN6145784)
Target
Alle PLOD1 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 488-727
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Sequenz
- RQQDVFMFLT NRHTLGHLLS LDSYRTTHLH NDLWEVFSNP EDWKEKYIHQ NYTKALAGKL VETPCPDVYW FPIFTEVACD ELVEEMEHFG QWSLGNNKDN RIQGGYENVP TIDIHMNQIG FEREWHKFLL EYIAPMTEKL YPGYYTRAQF DLAFVVRYKP DEQPSLMPHH DASTFTINIA LNRVGVDYEG GGCRFLRYNC SIRAPRKGWT LMHPGRLTHY HEGLPTTRGT RYIAVSFVDP
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Kreuzreaktivität
- Human, Maus, Ratte
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Produktmerkmale
- Polyclonal Antibodies
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Immunogen
- Recombinant fusion protein containing a sequence corresponding to amino acids 488-727 of human PLOD1 (NP_000293.2).
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Isotyp
- IgG
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Applikationshinweise
- WB,1:500 - 1:2000
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Kommentare
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HIGH QUALITY
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Store at -20°C. Avoid freeze / thaw cycles.
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- PLOD1 (Procollagen-Lysine,2-Oxoglutarate 5-Dioxygenase 1 (PLOD1))
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Andere Bezeichnung
- PLOD1
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Hintergrund
- Lysyl hydroxylase is a membrane-bound homodimeric protein localized to the cisternae of the endoplasmic reticulum. The enzyme (cofactors iron and ascorbate) catalyzes the hydroxylation of lysyl residues in collagen-like peptides. The resultant hydroxylysyl groups are attachment sites for carbohydrates in collagen and thus are critical for the stability of intermolecular crosslinks. Some patients with Ehlers-Danlos syndrome type VI have deficiencies in lysyl hydroxylase activity. Two transcript variants encoding different isoforms have been found for this gene.,PLOD1,EDS6,LH,LH1,LLH,PLOD,Epigenetics & Nuclear Signaling,Signal Transduction,Cell Biology & Developmental Biology,Cytoskeleton,Extracellular Matrix,Collagen,PLOD1
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Molekulargewicht
- 83 kDa/88 kDa
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Gen-ID
- 5351
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UniProt
- Q02809
Target
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