PIM1 Antikörper (AA 1-313)

Produktnummer ABIN6145653

Der Kaninchen Polyklonal anti-PIM1 Antikörper wird verwendet zum Nachweis von PIM1 in Proben von Human. Er wurde validiert für WB.

Kurzübersicht für PIM1 Antikörper (AA 1-313) (ABIN6145653)

Target: PIM1 (Pim-1 Oncogene (PIM1))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PIM1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-PIM1 Antikörper

Bindungsspezifität: AA 1-313

Sequenz: MLLSKINSLA HLRAAPCNDL HATKLAPGKE KEPLESQYQV GPLLGSGGFG SVYSGIRVSD NLPVAIKHVE KDRISDWGEL PNGTRVPMEV VLLKKVSSGF SGVIRLLDWF ERPDSFVLIL ERPEPVQDLF DFITERGALQ EELARSFFWQ VLEAVRHCHN CGVLHRDIKD ENILIDLNRG ELKLIDFGSG ALLKDTVYTD FDGTRVYSPP EWIRYHRYHG RSAAVWSLGI LLYDMVCGDI PFEHDEEIIR GQVFFRQRVS SECQHLIRWC LALRPSDRPT FEEIQNHPWM QDVLLPQETA EIHLHSLSPG PSK

Kreuzreaktivität: Ratte

Produktmerkmale: Polyclonal Antibodies

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-313 of human PIM1 (NP_002639.1).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB,1:500 - 1:2000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu PIM1

Target: PIM1 (Pim-1 Oncogene (PIM1))

Andere Bezeichnung: PIM1

Hintergrund: The protein encoded by this gene belongs to the Ser/Thr protein kinase family, and PIM subfamily. This gene is expressed primarily in B-lymphoid and myeloid cell lines, and is overexpressed in hematopoietic malignancies and in prostate cancer. It plays a role in signal transduction in blood cells, contributing to both cell proliferation and survival, and thus provides a selective advantage in tumorigenesis. Both the human and orthologous mouse genes have been reported to encode two isoforms (with preferential cellular localization) resulting from the use of alternative in-frame translation initiation codons, the upstream non-AUG (CUG) and downstream AUG codons (PMIDs:16186805, 1825810).,PIM,PIM1,PIM1,Epigenetics & Nuclear Signaling,Chromatin Modifying Enzymes,Phosphorylation,Chromatin Remodeling,Cancer,Signal Transduction,Kinase,Serine/threonine kinases,Cell Biology & Developmental Biology,Apoptosis,Immunology & Inflammation,IL-6 Receptor Signaling Pathway,Stem Cells,Hematopoietic Progenitors,PIM1

Molekulargewicht: 35 kDa/45 kDa

Gen-ID: 5292

UniProt: P11309

Pathways: Glycosaminoglycan Metabolic Process