PHKB Antikörper (AA 854-1093)

Produktnummer ABIN6145560

Dieses Anti-PHKB-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von PHKB in WB. Geeignet für Human.

Kurzübersicht für PHKB Antikörper (AA 854-1093) (ABIN6145560)

Target: PHKB (Phosphorylase Kinase, beta (PHKB))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PHKB Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-PHKB Antikörper

Bindungsspezifität: AA 854-1093

Sequenz: VIHIGWIISN NPELFSGMLK IRIGWIIHAM EYELQIRGGD KPALDLYQLS PSEVKQLLLD ILQPQQNGRC WLNRRQIDGS LNRTPTGFYD RVWQILERTP NGIIVAGKHL PQQPTLSDMT MYEMNFSLLV EDTLGNIDQP QYRQIVVELL MVVSIVLERN PELEFQDKVD LDRLVKEAFN EFQKDQSRLK EIEKQDDMTS FYNTPPLGKR GTCSYLTKAV MNLLLEGEVK PNNDDPCLIS

Kreuzreaktivität: Human, Maus

Produktmerkmale: Polyclonal Antibodies

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 854-1093 of human PHKB (NP_000284.1).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB,1:500 - 1:2000

Kommentare:

HIGH QUALITY

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu PHKB

Target: PHKB (Phosphorylase Kinase, beta (PHKB))

Andere Bezeichnung: PHKB

Hintergrund: Phosphorylase kinase is a polymer of 16 subunits, four each of alpha, beta, gamma and delta. The alpha subunit includes the skeletal muscle and hepatic isoforms, encoded by two different genes. The beta subunit is the same in both the muscle and hepatic isoforms, encoded by this gene, which is a member of the phosphorylase b kinase regulatory subunit family. The gamma subunit also includes the skeletal muscle and hepatic isoforms, encoded by two different genes. The delta subunit is a calmodulin and can be encoded by three different genes. The gamma subunits contain the active site of the enzyme, whereas the alpha and beta subunits have regulatory functions controlled by phosphorylation. The delta subunit mediates the dependence of the enzyme on calcium concentration. Mutations in this gene cause glycogen storage disease type 9B, also known as phosphorylase kinase deficiency of liver and muscle. Alternatively spliced transcript variants encoding different isoforms have been identified in this gene. Two pseudogenes have been found on chromosomes 14 and 20, respectively.,PHKB,Cancer,Signal Transduction,Endocrine & Metabolism,Carbohydrate metabolism,PHKB

Molekulargewicht: 123 kDa/124 kDa

Gen-ID: 5257

UniProt: Q93100

Pathways: Cellular Glucan Metabolic Process