PDE1A Antikörper (AA 446-545)
Kurzübersicht für PDE1A Antikörper (AA 446-545) (ABIN6145346)
Target
Alle PDE1A Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 446-545
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Sequenz
- EASKAETSSY VASSSTTIVG LHIADALRRS NTKGSMSDGS YSPDYSLAAV DLKSFKNNLV DIIQQNKERW KELAAQGESD LHKNSEDLVN AEEKHDETHS
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Kreuzreaktivität
- Human, Maus, Ratte
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Produktmerkmale
- Polyclonal Antibodies
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Immunogen
- Recombinant fusion protein containing a sequence corresponding to amino acids 446-545 of human PDE1A (NP_005010.2).
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Isotyp
- IgG
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Applikationshinweise
- WB,1:500 - 1:2000
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Kommentare
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HIGH QUALITY
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Store at -20°C. Avoid freeze / thaw cycles.
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- PDE1A (Phosphodiesterase 1A (PDE1A))
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Andere Bezeichnung
- PDE1A
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Hintergrund
- Cyclic nucleotide phosphodiesterases (PDEs) play a role in signal transduction by regulating intracellular cyclic nucleotide concentrations through hydrolysis of cAMP and/or cGMP to their respective nucleoside 5-prime monophosphates. Members of the PDE1 family, such as PDE1A, are Ca(2+)/calmodulin (see CALM1, MIM 114180)-dependent PDEs (CaM-PDEs) that are activated by calmodulin in the presence of Ca(2+) (Michibata et al., 2001 [PubMed 11342109], Fidock et al., 2002 [PubMed 11747989]).[supplied by OMIM, Oct 2009],PDE1A,CAM-PDE-1A,HCAM-1,HCAM1,HSPDE1A,PDE1A
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Molekulargewicht
- 57 kDa/58 kDa/59 kDa/60 kDa/61 kDa/62 kDa/63 kDa
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Gen-ID
- 5136
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UniProt
- P54750
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Pathways
- Neurotrophin Signalübertragung, cAMP Metabolic Process, G-protein mediated Events, Interaction of EGFR with phospholipase C-gamma
Target
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