PBXIP1 Antikörper (AA 1-190)
Kurzübersicht für PBXIP1 Antikörper (AA 1-190) (ABIN6145273)
Target
Alle PBXIP1 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 1-190
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Sequenz
- MASCPDSDNS WVLAGSESLP VETLGPASRM DPESERALQA PHSPSKTDGK ELAGTMDGEG TLFQTESPQS GSILTEETEV KGTLEGDVCG VEPPGPGDTV VQGDLQETTV VTGLGPDTQD LEGQSPPQSL PSTPKAAWIR EEGRCSSSDD DTDVDMEGLR RRRGREAGPP QPMVPLAVEN QAGGEGAGGE
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Kreuzreaktivität
- Human, Maus, Ratte
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Produktmerkmale
- Polyclonal Antibodies
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Immunogen
- Recombinant fusion protein containing a sequence corresponding to amino acids 1-190 of human PBXIP1 (NP_065385.2).
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Isotyp
- IgG
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Applikationshinweise
- WB,1:1000 - 1:2000,IHC,1:50 - 1:200
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Kommentare
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HIGH QUALITY
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Store at -20°C. Avoid freeze / thaw cycles.
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- PBXIP1 (Pre-B-Cell Leukemia Homeobox Interacting Protein 1 (PBXIP1))
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Andere Bezeichnung
- PBXIP1
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Hintergrund
- The protein encoded by this gene interacts with the PBX1 homeodomain protein, inhibiting its transcriptional activation potential by preventing its binding to DNA. The encoded protein, which is primarily cytosolic but can shuttle to the nucleus, also can interact with estrogen receptors alpha and beta and promote the proliferation of breast cancer, brain tumors, and lung cancer. Several transcript variants encoding different isoforms have been found for this gene. More variants exist, but their full-length natures have yet to be determined.,PBXIP1,HPIP,Epigenetics & Nuclear Signaling,Nuclear Receptor Signaling,Nuclear hormone receptors,Signal Transduction,PBXIP1
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Molekulargewicht
- 72 kDa/77 kDa/80 kDa
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Gen-ID
- 57326
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UniProt
- Q96AQ6
Target
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