Occludin Antikörper (AA 263-522)

Produktnummer ABIN6144996

Dieses Anti-Occludin-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von Occludin in WB. Geeignet für Human. Dieses Primary Antibody wurde in 1 Publikation zitiert.

Kurzübersicht für Occludin Antikörper (AA 263-522) (ABIN6144996)

Target: Occludin (OCLN)

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Occludin Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-Occludin Antikörper

Bindungsspezifität: AA 263-522

Sequenz: FAVKTRRKMD RYDKSNILWD KEHIYDEQPP NVEEWVKNVS AGTQDVPSPP SDYVERVDSP MAYSSNGKVN DKRFYPESSY KSTPVPEVVQ ELPLTSPVDD FRQPRYSSGG NFETPSKRAP AKGRAGRSKR TEQDHYETDY TTGGESCDEL EEDWIREYPP ITSDQQRQLY KRNFDTGLQE YKSLQSELDE INKELSRLDK ELDDYREESE EYMAAADEYN RLKQVKGSAD YKSKKNHCKQ LKSKLSHIKK MVGDYDRQKT

Kreuzreaktivität: Human, Maus, Ratte

Produktmerkmale: Polyclonal Antibodies

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 263-522 of human Occludin (NP_002529.1).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB,1:1000 - 1:2000

Kommentare:

HIGH QUALITY

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Referenzen für anti-Occludin Antikörper (ABIN6144996)

Knowlton, Fernández de Castro, Ashbrook, Gestaut, Zamora, Bauer, Forrest, Frydman, Risco, Dermody: "The TRiC chaperonin controls reovirus replication through outer-capsid folding." in: Nature microbiology, Vol. 3, Issue 4, pp. 481-493, (2018) (PubMed).

Details zu Occludin

Target: Occludin (OCLN)

Andere Bezeichnung: OCLN

Hintergrund: This gene encodes an integral membrane protein that is required for cytokine-induced regulation of the tight junction paracellular permeability barrier. Mutations in this gene are thought to be a cause of band-like calcification with simplified gyration and polymicrogyria (BLC-PMG), an autosomal recessive neurologic disorder that is also known as pseudo-TORCH syndrome. Alternative splicing results in multiple transcript variants. A related pseudogene is present 1.5 Mb downstream on the q arm of chromosome 5.,OCLN,BLCPMG,PPP1R115,PTORCH1,occludin,Occludin,Signal Transduction,Cell Biology & Developmental Biology,Apoptosis,Cell Adhesion,Tight Junctions,Cytoskeleton,OCLN

Molekulargewicht: 8 kDa/23 kDa/31 kDa/52 kDa/54 kDa/59 kDa

Gen-ID: 100506658

UniProt: Q16625

Pathways: Cell-Cell Junction Organization, Hepatitis C