Occludin Antikörper (AA 350-450)
Quick Overview for Occludin Antikörper (AA 350-450) (ABIN6144995)
Target
Alle Occludin (OCLN) Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 350-450
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Sequenz
- VVQELPLTSP VDDFRQPRYS SGGNFETPSK RAPAKGRAGR SKRTEQDHYE TDYTTGGESC DELEEDWIRE YPPITSDQQR QLYKRNFDTG LQEYKSLQSE L
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Kreuzreaktivität
- Human, Maus, Ratte
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Produktmerkmale
- Polyclonal Antibodies
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Immunogen
- Recombinant fusion protein containing a sequence corresponding to amino acids 350-450 of human Occludin (NP_002529.1).
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Isotyp
- IgG
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Applikationshinweise
- WB,1:500 - 1:2000
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Store at -20°C. Avoid freeze / thaw cycles.
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- Occludin (OCLN)
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Andere Bezeichnung
- OCLN
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Hintergrund
- This gene encodes an integral membrane protein that is required for cytokine-induced regulation of the tight junction paracellular permeability barrier. Mutations in this gene are thought to be a cause of band-like calcification with simplified gyration and polymicrogyria (BLC-PMG), an autosomal recessive neurologic disorder that is also known as pseudo-TORCH syndrome. Alternative splicing results in multiple transcript variants. A related pseudogene is present 1.5 Mb downstream on the q arm of chromosome 5.,OCLN,BLCPMG,PPP1R115,PTORCH1,occludin,Occludin,Signal Transduction,Cell Biology & Developmental Biology,Apoptosis,Cell Adhesion,Tight Junctions,Cytoskeleton,OCLN
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Molekulargewicht
- 8 kDa/23 kDa/31 kDa/52 kDa/54 kDa/59 kDa
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Gen-ID
- 100506658
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UniProt
- Q16625
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Pathways
- Cell-Cell Junction Organization, Hepatitis C
Target
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