NPRL2 Antikörper (AA 1-220)
Kurzübersicht für NPRL2 Antikörper (AA 1-220) (ABIN6144787)
Target
Alle NPRL2 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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    - 
                                            Bindungsspezifität
- AA 1-220
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                                            Sequenz
- MGSGCRIECI FFSEFHPTLG PKITYQVPED FISRELFDTV QVYIITKPEL QNKLITVTAM EKKLIGCPVC IEHKKYSRNA LLFNLGFVCD AQAKTCALEP IVKKLAGYLT TLELESSFVS MEESKQKLVP IMTILLEELN ASGRCTLPID ESNTIHLKVI EQRPDPPVAQ EYDVPVFTKD KEDFFNSQWD LTTQQILPYI DGFRHIQKIS AEADVELNLV
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                                            Kreuzreaktivität
- Human, Maus, Ratte
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                                            Produktmerkmale
- Polyclonal Antibodies
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                                            Immunogen
- Recombinant fusion protein containing a sequence corresponding to amino acids 1-220 of human NPRL2 (NP_006536.3).
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                                            Isotyp
- IgG
 
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    - 
                                            Applikationshinweise
- WB,1:500 - 1:2000,IF,1:50 - 1:200
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                                            Kommentare
- 
                        HIGH QUALITY 
- 
                                            Beschränkungen
- Nur für Forschungszwecke einsetzbar
 
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    - 
                                            Format
- Liquid
- 
                                            Buffer
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
- 
                                            Konservierungsmittel
- Sodium azide
- 
                                            Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 
                                            Lagerung
- -20 °C
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                                            Informationen zur Lagerung
- Store at -20°C. Avoid freeze / thaw cycles.
 
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    - NPRL2 (Nitrogen Permease Regulator-Like 2 (S. Cerevisiae) (NPRL2))
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                                            Andere Bezeichnung
- NPRL2
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                                            Hintergrund
- As a component of the GATOR1 complex functions as an inhibitor of the amino acid-sensing branch of the TORC1 pathway. The GATOR1 complex strongly increases GTP hydrolysis by RRAGA and RRAGB within RRAGC-containing heterodimers, thereby deactivating RRAGs, releasing mTORC1 from lysosomal surface and inhibiting mTORC1 signaling. The GATOR1 complex is negatively regulated by GATOR2 the other GATOR subcomplex in this amino acid-sensing branch of the TORC1 pathway.,NPRL2,FFEVF2,NPR2,NPR2L,TUSC4,NPR2-like,Epigenetics & Nuclear Signaling,Cancer,Tumor suppressors,Cell Biology & Developmental Biology,Apoptosis,NPRL2
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                                            Molekulargewicht
- 23 kDa/43 kDa
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                                            Gen-ID
- 10641
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                                            UniProt
- Q8WTW4
 Target
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