Nodal Antikörper (AA 198-347)

Produktnummer ABIN6144699

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch Nodal in WB. Er zeigt eine Reaktivität gegenüber Human.

Kurzübersicht für Nodal Antikörper (AA 198-347) (ABIN6144699)

Target: Nodal (NODAL) (Nodal Homolog (NODAL))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Nodal Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-Nodal Antikörper

Bindungsspezifität: AA 198-347

Sequenz: SNLSQEQRQL GGSTLLWEAE SSWRAQEGQL SWEWGKRHRR HHLPDRSQLC RKVKFQVDFN LIGWGSWIIY PKQYNAYRCE GECPNPVGEE FHPTNHAYIQ SLLKRYQPHR VPSTCCAPVK TKPLSMLYVD NGRVLLDHHK DMIVEECGCL

Kreuzreaktivität: Human, Ratte

Produktmerkmale: Polyclonal Antibodies

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 198-347 of human NODAL (NP_060525.3).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB,1:500 - 1:2000

Kommentare:

HIGH QUALITY

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu Nodal

Target: Nodal (NODAL) (Nodal Homolog (NODAL))

Andere Bezeichnung: NODAL

Hintergrund: This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate the mature protein, which regulates early embryonic development. This protein is required for maintenance of human embryonic stem cell pluripotency and may play a role in human placental development. Mutations in this gene are associated with heterotaxy, a condition characterized by random orientation of visceral organs with respect to the left-right axis.,NODAL,HTX5,Cell Biology & Developmental Biology,Growth factor,TGF-b-Smad Signaling Pathway,ESC Pluripotency and Differentiation,Immunology & Inflammation,Cytokines,Stem Cells,Embryonic Stem Cells,Ligand,NODAL

Molekulargewicht: 39 kDa

Gen-ID: 4838

UniProt: Q96S42

Pathways: Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling, Stem Cell Maintenance, Tube Formation, Positive Regulation of Endopeptidase Activity