CD1d Antikörper
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- Target Alle CD1d (CD1D) Antikörper anzeigen
- CD1d (CD1D) (CD1d Molecule (CD1D))
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Reaktivität
- Human
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Wirt
- Maus
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Klonalität
- Monoklonal
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Konjugat
- Dieser CD1d Antikörper ist unkonjugiert
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Applikation
- Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
- Spezifität
- The monoclonal antibody reacts with Human CD1d.
- Kreuzreaktivität (Details)
- Species reactivity (tested):Human.
- Aufreinigung
- Affinity Chromatography
- Immunogen
- Human CD1d
- Klon
- 51-1
- Isotyp
- IgG2b
- Top Product
- Discover our top product CD1D Primärantikörper
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- Applikationshinweise
- Optimal working dilution should be determined by the investigator.
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Konzentration
- 0.5 mg/mL
- Buffer
- PBS, pH 7.2 containing < / = 0.09 % Sodium Azide as preservative
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handhabung
- Avoid repeated freezing and thawing.
- Lagerung
- 4 °C
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- Target
- CD1d (CD1D) (CD1d Molecule (CD1D))
- Andere Bezeichnung
- CD1d (CD1D Produkte)
- Hintergrund
- Human CD1d, a member of the CD1 family with similarity to the non-polymorphic MHC Class I-like molecules. CD1d is a highly conserved single transmembrane receptor of the Immunoglobulin Superfamily. CD1d can associate with beta-microglobulin another feature showing similarity to MHC class I molecules, but can also exist as a nonglycosylated protein not in association with beta microglobulin. This suggests different control mechanisms for presenting glycolipid containing molecules to CD1d reactive NKT cells. Expression of CD1d is found on B cells of the periphery, in resting monocytes and cortical thymocytes. On intestinal epithelial cells (IEC) expression is polarized. Expression can also be found at low levels intracellularly in hepatocytes. In HCV (hepatitis C virus) livers, CD1d is highly expressed compared to normal controls.Synonyms: R3G1, T-cell surface glycoprotein CD1d
- Gen-ID
- 912
- NCBI Accession
- NP_001757
- UniProt
- P15813
- Pathways
- Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process
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