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NAA50 Antikörper (AA 1-169)

Der Kaninchen Polyklonal Anti-NAA50-Antikörper wurde für WB und IF validiert. Er ist geeignet, NAA50 in Proben von Human zu detektieren.
Produktnummer ABIN6144327

Kurzübersicht für NAA50 Antikörper (AA 1-169) (ABIN6144327)

Target

Alle NAA50 Antikörper anzeigen
NAA50 (N(alpha)-Acetyltransferase 50, NatE Catalytic Subunit (NAA50))

Reaktivität

  • 18
  • 5
  • 5
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
Human

Wirt

  • 18
Kaninchen

Klonalität

  • 18
Polyklonal

Konjugat

  • 13
  • 1
  • 1
  • 1
  • 1
  • 1
Dieser NAA50 Antikörper ist unkonjugiert

Applikation

  • 16
  • 9
  • 9
  • 3
  • 3
  • 2
  • 1
Western Blotting (WB), Immunofluorescence (IF)
  • Bindungsspezifität

    • 8
    • 4
    • 2
    • 2
    • 1
    AA 1-169

    Sequenz

    MKGSRIELGD VTPHNIKQLK RLNQVIFPVS YNDKFYKDVL EVGELAKLAY FNDIAVGAVC CRVDHSQNQK RLYIMTLGCL APYRRLGIGT KMLNHVLNIC EKDGTFDNIY LHVQISNESA IDFYRKFGFE IIETKKNYYK RIEPADAHVL QKNLKVPSGQ NADVQKTDN

    Kreuzreaktivität

    Human, Maus, Ratte

    Produktmerkmale

    Polyclonal Antibodies

    Immunogen

    Recombinant fusion protein containing a sequence corresponding to amino acids 1-169 of human NAA50 (NP_079422.1).

    Isotyp

    IgG
  • Applikationshinweise

    WB,1:500 - 1:2000,IF,1:50 - 1:200

    Kommentare

    HIGH QUALITY

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Liquid

    Buffer

    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

    Konservierungsmittel

    Sodium azide

    Vorsichtsmaßnahmen

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Lagerung

    -20 °C

    Informationen zur Lagerung

    Store at -20°C. Avoid freeze / thaw cycles.
  • Target

    NAA50 (N(alpha)-Acetyltransferase 50, NatE Catalytic Subunit (NAA50))

    Andere Bezeichnung

    NAA50

    Hintergrund

    N-alpha-acetyltransferase that acetylates the N-terminus of proteins that retain their initiating methionine. Has a broad substrate specificity: able to acetylate the initiator methionine of most peptides, except for those with a proline in second position. Also displays N-epsilon-acetyltransferase activity by mediating acetylation of the side chain of specific lysines on proteins. Autoacetylates in vivo. The relevance of N-epsilon-acetyltransferase activity is however unclear: able to acetylate H4 in vitro, but this result has not been confirmed in vivo. Component of N-alpha-acetyltransferase complexes containing NAA10 and NAA15, which has N-alpha-acetyltransferase activity. Does not influence the acetyltransferase activity of NAA10. However, it negatively regulates the N-alpha-acetyltransferase activity of the N-terminal acetyltransferase A complex (also called the NatA complex. The multiprotein complexes probably constitute the major contributor for N-terminal acetylation at the ribosome exit tunnel, with NAA10 acetylating all amino termini that are devoid of methionine and NAA50 acetylating other peptides. Required for sister chromatid cohesion during mitosis by promoting binding of CDCA5/sororin to cohesin: may act by counteracting the function of NAA10.,NAA50,MAK3,NAT13,NAT13P,NAT5,NAT5P,SAN,Epigenetics & Nuclear Signaling,Cell Biology & Developmental Biology,NAA50

    Molekulargewicht

    9 kDa/19 kDa

    Gen-ID

    80218

    UniProt

    Q9GZZ1
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