Myosin VI Antikörper (AA 1016-1285)
Kurzübersicht für Myosin VI Antikörper (AA 1016-1285) (ABIN6144291)
Target
Alle Myosin VI (MYO6) Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 1016-1285
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Sequenz
- IAQSEAELIS DEAQADLALR RNDGTRPKMT PEQMAKEMSE FLSRGPAVLA TKAAAGTKKY DLSKWKYAEL RDTINTSCDI ELLAACREEF HRRLKVYHAW KSKNKKRNTE TEQRAPKSVT DYDFAPFLNN SPQQNPAAQI PARQREIEMN RQQRFFRIPF IRPADQYKDP QSKKKGWWYA HFDGPWIARQ MELHPDKPPI LLVAGKDDME MCELNLEETG LTRKRGAEIL PRQFEEIWER CGGIQYLQNA IESRQARPTY ATAMLQSLLK
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Kreuzreaktivität
- Human, Maus, Ratte
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Produktmerkmale
- Polyclonal Antibodies
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Immunogen
- Recombinant fusion protein containing a sequence corresponding to amino acids 1016-1285 of human MYO6 (NP_004990.3).
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Isotyp
- IgG
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Applikationshinweise
- WB,1:500 - 1:2000
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Store at -20°C. Avoid freeze / thaw cycles.
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- Myosin VI (MYO6)
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Andere Bezeichnung
- MYO6
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Hintergrund
- This gene encodes a reverse-direction motor protein that moves toward the minus end of actin filaments and plays a role in intracellular vesicle and organelle transport. The protein consists of a motor domain containing an ATP- and an actin-binding site and a globular tail which interacts with other proteins. This protein maintains the structural integrity of inner ear hair cells and mutations in this gene cause non-syndromic autosomal dominant and recessive hearing loss. Alternative splicing results in multiple transcript variants encoding distinct isoforms.,MYO6,DFNA22,DFNB37,Myo6-007,Myo6-008,myosin VI,Signal Transduction,Cell Biology & Developmental Biology,Cytoskeleton,Motor Proteins,MYO6
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Molekulargewicht
- 145 kDa/146 kDa/148 kDa/149 kDa
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Gen-ID
- 4646
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UniProt
- Q9UM54
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Pathways
- Sensory Perception of Sound, Dicarboxylic Acid Transport, Asymmetric Protein Localization
Target
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