MXI1 Antikörper (AA 170-295)

Produktnummer ABIN6144206

Der Kaninchen Polyklonal Anti-MXI1-Antikörper wurde für WB validiert. Er ist geeignet, MXI1 in Proben von Human zu detektieren.

Kurzübersicht für MXI1 Antikörper (AA 170-295) (ABIN6144206)

Target: MXI1 (MAX Interactor 1 (MXI1))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser MXI1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-MXI1 Antikörper

Bindungsspezifität: AA 170-295

Sequenz: HTTLGLLNKA KAHIKKLEEA ERKSQHQLEN LEREQRFLKW RLEQLQGPQE MERIRMDSIG STISSDRSDS EREEIEVDVE STEFSHGEVD NISTTSISDI DDHSSLPSIG SDEGYSSASV KLSFTS

Kreuzreaktivität: Human, Maus, Ratte

Produktmerkmale: Polyclonal Antibodies

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 170-295 of human MXI1 (NP_569157.2).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB,1:500 - 1:2000

Kommentare:

HIGH QUALITY

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu MXI1

Target: MXI1 (MAX Interactor 1 (MXI1))

Andere Bezeichnung: MXI1

Hintergrund: Expression of the c-myc gene, which produces an oncogenic transcription factor, is tightly regulated in normal cells but is frequently deregulated in human cancers. The protein encoded by this gene is a transcriptional repressor thought to negatively regulate MYC function, and is therefore a potential tumor suppressor. This protein inhibits the transcriptional activity of MYC by competing for MAX, another basic helix-loop-helix protein that binds to MYC and is required for its function. Defects in this gene are frequently found in patients with prostate tumors. Three alternatively spliced transcripts encoding different isoforms have been described. Additional alternatively spliced transcripts may exist but the products of these transcripts have not been verified experimentally.,MXI1,MAD2,MXD2,MXI,bHLHc11,Epigenetics & Nuclear Signaling,Transcription Factors,MXI1

Molekulargewicht: 20 kDa/21 kDa/26 kDa/32 kDa

Gen-ID: 4601

UniProt: P50539

Pathways: Maintenance of Protein Location