PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
Konservierungsmittel
Sodium azide
Vorsichtsmaßnahmen
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung
-20 °C
Informationen zur Lagerung
Store at -20°C. Avoid freeze / thaw cycles.
Target
MTDH
(Metadherin (MTDH))
Andere Bezeichnung
MTDH
Hintergrund
Downregulates SLC1A2/EAAT2 promoter activity when expressed ectopically. Activates the nuclear factor kappa-B (NF-kappa-B transcription factor. Promotes anchorage-independent growth of immortalized melanocytes and astrocytes which is a key component in tumor cell expansion. Promotes lung metastasis and also has an effect on bone and brain metastasis, possibly by enhancing the seeding of tumor cells to the target organ endothelium. Induces chemoresistance.,MTDH,3D3,AEG-1,AEG1,LYRIC,LYRIC/3D3,Epigenetics & Nuclear Signaling,RNA Binding,Cancer,Signal Transduction,Cell Biology & Developmental Biology,Cell Adhesion,Tight Junctions,Cytoskeleton,Microfilaments,MTDH