MSL2 Antikörper (AA 328-577)
Kurzübersicht für MSL2 Antikörper (AA 328-577) (ABIN6144069)
Target
Alle MSL2 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 328-577
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Sequenz
- CTAATPKIAK LNRKRSRSES DSEKVQPLPI STIIRGPTLG ASAPVTVKRE SKISLQPIAT VPNGGTTPKI SKTVLLSTKS MKKSHEHGSK KSHSKTKPGI LKKDKAVKEK IPSHHFMPGS PTKTVYKKPQ EKKGCKCGRA TQNPSVLTCR GQRCPCYSNR KACLDCICRG CQNSYMANGE KKLEAFAVPE KALEQTRLTL GINVTSIAVR NASTSTSVIN VTGSPVTTFL AASTHDDKSL DEAIDMRFDC
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Kreuzreaktivität
- Human, Maus, Ratte
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Produktmerkmale
- Polyclonal Antibodies
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Immunogen
- Recombinant fusion protein containing a sequence corresponding to amino acids 328-577 of human MSL2 (NP_060603.2).
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Isotyp
- IgG
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Applikationshinweise
- WB,1:500 - 1:2000
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Store at -20°C. Avoid freeze / thaw cycles.
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- MSL2 (Male-Specific Lethal 2 Homolog (MSL2))
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Andere Bezeichnung
- MSL2
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Hintergrund
- Component of histone acetyltransferase complex responsible for the majority of histone H4 acetylation at lysine 16 which is implicated in the formation of higher-order chromatin structure. Acts as an E3 ubiquitin ligase that promotes monoubiquitination of histone H2B at 'Lys-35' (H2BK34Ub, but not that of H2A. This activity is greatly enhanced by heterodimerization with MSL1. H2B ubiquitination in turn stimulates histone H3 methylation at 'Lys-4' (H3K4me and 'Lys-79' (H3K79me and leads to gene activation, including that of HOXA9 and MEIS1.,MSL2,MSL-2,MSL2L1,RNF184,Epigenetics & Nuclear Signaling,MSL2
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Molekulargewicht
- 54 kDa/62 kDa
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Gen-ID
- 55167
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UniProt
- Q9HCI7
Target
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