MECOM Antikörper (AA 1-120)
Kurzübersicht für MECOM Antikörper (AA 1-120) (ABIN6143677)
Target
Alle MECOM Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 1-120
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Sequenz
- MRSKGRARKL ATNNECVYGN YPEIPLEEMP DADGVASTPS LNIQEPCSPA TSSEAFTPKE GSPYKAPIYI PDDIPIPAEF ELRESNMPGA GLGIWTKRKI EVGEKFGPYV GEQRSNLKDP
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Kreuzreaktivität
- Maus
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Produktmerkmale
- Polyclonal Antibodies
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Immunogen
- Recombinant fusion protein containing a sequence corresponding to amino acids 1-120 of human MECOM (NP_004982.2).
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Isotyp
- IgG
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Applikationshinweise
- WB,1:500 - 1:2000
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Kommentare
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HIGH QUALITY
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Store at -20°C. Avoid freeze / thaw cycles.
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- MECOM (MDS1 and EVI1 Complex Locus (MECOM))
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Andere Bezeichnung
- MECOM
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Hintergrund
- The protein encoded by this gene is a transcriptional regulator and oncoprotein that may be involved in hematopoiesis, apoptosis, development, and cell differentiation and proliferation. The encoded protein can interact with CTBP1, SMAD3, CREBBP, KAT2B, MAPK8, and MAPK9. This gene can undergo translocation with the AML1 gene, resulting in overexpression of this gene and the onset of leukemia. Several transcript variants encoding a few different isoforms have been found for this gene.,MECOM,AML1-EVI-1,EVI1,KMT8E,MDS1,MDS1-EVI1,PRDM3,RUSAT2,Epigenetics & Nuclear Signaling,Cell Biology & Developmental Biology,Cell Cycle,Cell differentiation,MECOM
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Molekulargewicht
- 18 kDa/117 kDa/118 kDa/125 kDa/139 kDa
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Gen-ID
- 2122
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UniProt
- Q03112, Q13465
Target
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