MDC1 Antikörper (AA 1-100)
Kurzübersicht für MDC1 Antikörper (AA 1-100) (ABIN6143659)
Target
Alle MDC1 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 1-100
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Sequenz
- MEDTQAIDWD VEEEEETEQS SESLRCNVEP VGRLHIFSGA HGPEKDFPLH LGKNVVGRMP DCSVALPFPS ISKQHAEIEI LAWDKAPILR DCGSLNGTQI
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Kreuzreaktivität
- Human, Maus
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Produktmerkmale
- Polyclonal Antibodies
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Immunogen
- A synthetic peptide corresponding to a sequence within amino acids 1-100 of human MDC1 (NP_055456.2).
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Isotyp
- IgG
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Applikationshinweise
- WB,1:500 - 1:2000,IHC,1:50 - 1:200,IF,1:50 - 1:200
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Store at -20°C. Avoid freeze / thaw cycles.
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- MDC1 (Mdc1 (MDC1))
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Andere Bezeichnung
- MDC1
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Hintergrund
- The protein encoded by this gene contains an N-terminal forkhead domain, two BRCA1 C-terminal (BRCT) motifs and a central domain with 13 repetitions of an approximately 41-amino acid sequence. The encoded protein is required to activate the intra-S phase and G2/M phase cell cycle checkpoints in response to DNA damage. This nuclear protein interacts with phosphorylated histone H2AX near sites of DNA double-strand breaks through its BRCT motifs, and facilitates recruitment of the ATM kinase and meiotic recombination 11 protein complex to DNA damage foci.,MDC1,NFBD1,Epigenetics & Nuclear Signaling,DNA Damage & Repair,MDC1
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Molekulargewicht
- 116 kDa/195 kDa/197 kDa/226 kDa
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Gen-ID
- 9656
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UniProt
- Q14676
Target
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