MCM10 Antikörper (AA 616-875)

Produktnummer ABIN6143639

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch MCM10 in WB. Er zeigt eine Reaktivität gegenüber Human.

Kurzübersicht für MCM10 Antikörper (AA 616-875) (ABIN6143639)

Target: MCM10 (Minichromosome Maintenance Deficient 10 (MCM10))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser MCM10 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-MCM10 Antikörper

Bindungsspezifität: AA 616-875

Sequenz: RLEGAPATMT PKLGRGVLEG DDVLFYDESP PPRPKLSALA EAKKLAAITK LRAKGQVLTK TNPNSIKKKQ KDPQDILEVK ERVEKNTMFS SQAEDELEPA RKKRREQLAY LESEEFQKIL KAKSKHTGIL KEAEAEMQER YFEPLVKKEQ MEEKMRNIRE VKCRVVTCKT CAYTHFKLLE TCVSEQHEYH WHDGVKRFFK CPCGNRSISL DRLPNKHCSN CGLYKWERDG MLKEKTGPKI GGETLLPRGE EHAKFLNSLK

Kreuzreaktivität: Human, Maus, Ratte

Produktmerkmale: Polyclonal Antibodies

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 616-875 of human MCM10 (NP_877428.1).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB,1:500 - 1:2000

Kommentare:

HIGH QUALITY

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu MCM10

Target: MCM10 (Minichromosome Maintenance Deficient 10 (MCM10))

Andere Bezeichnung: MCM10

Hintergrund: The protein encoded by this gene is one of the highly conserved mini-chromosome maintenance proteins (MCM) that are involved in the initiation of eukaryotic genome replication. The hexameric protein complex formed by MCM proteins is a key component of the pre-replication complex (pre-RC) and it may be involved in the formation of replication forks and in the recruitment of other DNA replication related proteins. This protein can interact with MCM2 and MCM6, as well as with the origin recognition protein ORC2. It is regulated by proteolysis and phosphorylation in a cell cycle-dependent manner. Studies of a similar protein in Xenopus suggest that the chromatin binding of this protein at the onset of DNA replication is after pre-RC assembly and before origin unwinding. Alternatively spliced transcript variants encoding distinct isoforms have been identified.,MCM10,CNA43,DNA43,PRO2249,Epigenetics & Nuclear Signaling,MCM10

Molekulargewicht: 98 kDa

Gen-ID: 55388

UniProt: Q7L590

Pathways: Mitotic G1-G1/S Phases, DNA Replication