LY6E Antikörper (AA 21-101)

Produktnummer ABIN6143391

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch LY6E in WB und IF. Er zeigt eine Reaktivität gegenüber Human.

Kurzübersicht für LY6E Antikörper (AA 21-101) (ABIN6143391)

Target: LY6E (Lymphocyte Antigen 6 Complex, Locus E (LY6E))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser LY6E Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (IF)

Produktdetails anti-LY6E Antikörper

Bindungsspezifität: AA 21-101

Sequenz: LMCFSCLNQK SNLYCLKPTI CSDQDNYCVT VSASAGIGNL VTFGHSLSKT CSPACPIPEG VNVGVASMGI SCCQSFLCNF S

Kreuzreaktivität: Human, Maus

Produktmerkmale: Polyclonal Antibodies

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 21-101 of human LY6E (NP_002337.1).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB,1:1000 - 1:2000,IF,1:50 - 1:200

Kommentare:

HIGH QUALITY

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu LY6E

Target: LY6E (Lymphocyte Antigen 6 Complex, Locus E (LY6E))

Andere Bezeichnung: LY6E

Hintergrund: GPI-anchored cell surface protein that regulates T-lymphocytes proliferation, differentiation, and activation. Regulates the T-cell receptor (TCR signaling by interacting with component CD3Z/CD247 at the plasma membrane, leading to CD3Z/CD247 phosphorylation modulation (By similarity. Restricts the entry of human coronaviruses, including SARS-CoV, MERS-CoV and SARS-CoV-2, by interfering with spike protein-mediated membrane fusion. Plays also an essential role in placenta formation by acting as the main receptor for syncytin-A (SynA. Therefore, participates in the normal fusion of syncytiotrophoblast layer I (SynT-I and in the proper morphogenesis of both fetal and maternal vasculatures within the placenta. May also act as a modulator of nicotinic acetylcholine receptors (nAChRs activity (By similarity.,LY6E,RIG-E,RIGE,SCA-2,SCA2,TSA-1,LY6E

Molekulargewicht: 13 kDa

Gen-ID: 4061

UniProt: Q16553

Pathways: Hormone Transport