Lipin 1 Antikörper (AA 741-890)

Produktnummer ABIN6143300

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch Lipin 1 in WB. Er zeigt eine Reaktivität gegenüber Human.

Kurzübersicht für Lipin 1 Antikörper (AA 741-890) (ABIN6143300)

Target: Lipin 1 (LPIN1)

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Lipin 1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-Lipin 1 Antikörper

Bindungsspezifität: AA 741-890

Sequenz: NERGTVLPQG PLLLSPSSLF SALHREVIEK KPEKFKVQCL TDIKNLFFPN TEPFYAAFGN RPADVYSYKQ VGVSLNRIFT VNPKGELVQE HAKTNISSYV RLCEVVDHVF PLLKRSHSSD FPCSDTFSNF TFWREPLPPF ENQDIHSASA

Kreuzreaktivität: Ratte

Produktmerkmale: Polyclonal Antibodies

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 741-890 of human Lipin 1 (NP_663731.1).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB,1:500 - 1:2000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu Lipin 1

Target: Lipin 1 (LPIN1)

Andere Bezeichnung: LPIN1

Hintergrund: This gene encodes a magnesium-ion-dependent phosphatidic acid phosphohydrolase enzyme that catalyzes the penultimate step in triglyceride synthesis including the dephosphorylation of phosphatidic acid to yield diacylglycerol. Expression of this gene is required for adipocyte differentiation and it also functions as a nuclear transcriptional coactivator with some peroxisome proliferator-activated receptors to modulate expression of other genes involved in lipid metabolism. Mutations in this gene are associated with metabolic syndrome, type 2 diabetes, and autosomal recessive acute recurrent myoglobinuria (ARARM). This gene is also a candidate for several human lipodystrophy syndromes. Alternative splicing results in multiple transcript variants encoding distinct isoforms. Additional splice variants have been described but their full-length structures have not been determined.,LPIN1,PAP1,lipin 1,Signal Transduction,Cell Biology & Developmental Biology,Cell Cycle,Cell differentiation,Endocrine & Metabolism,Lipid Metabolism,Cholesterol Metabolism,Endocrine and metabolic diseases,Diabetes,Cardiovascular,Heart,Lipids,Cardiovascular diseases,Heart disease,LPIN1

Molekulargewicht: 50 kDa/98 kDa/99-107 kDa

Gen-ID: 23175

UniProt: Q14693

Pathways: Monocarboxylic Acid Catabolic Process