LMAN1 Antikörper (AA 270-480)
Kurzübersicht für LMAN1 Antikörper (AA 270-480) (ABIN6143266)
Target
Alle LMAN1 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 270-480
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Sequenz
- PGKEPPTPDK EISEKEKEKY QEEFEHFQQE LDKKKEEFQK GHPDLQGQPA EEIFESVGDR ELRQVFEGQN RIHLEIKQLN RQLDMILDEQ RRYVSSLTEE ISKRGAGMPG QHGQITQQEL DTVVKTQHEI LRQVNEMKNS MSETVRLVSG MQHPGSAGGV YETTQHFIDI KEHLHIVKRD IDNLVQRNMP SNEKPKCPEL PPFPSCLSTV H
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Kreuzreaktivität
- Human, Maus, Ratte
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Produktmerkmale
- Polyclonal Antibodies
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Immunogen
- Recombinant fusion protein containing a sequence corresponding to amino acids 270-480 of human LMAN1 (NP_005561.1).
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Isotyp
- IgG
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Applikationshinweise
- WB,1:500 - 1:2000,IHC,1:50 - 1:100,IF,1:50 - 1:200
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Kommentare
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HIGH QUALITY
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Store at -20°C. Avoid freeze / thaw cycles.
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- LMAN1 (Lectin, Mannose-Binding, 1 (LMAN1))
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Andere Bezeichnung
- LMAN1
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Hintergrund
- The protein encoded by this gene is a membrane mannose-specific lectin that cycles between the endoplasmic reticulum, endoplasmic reticulum-Golgi intermediate compartment, and cis-Golgi, functioning as a cargo receptor for glycoprotein transport. The protein has an N-terminal signal sequence, a calcium-dependent and pH -sensitive carbohydrate recognition domain, a stalk region that functions in oligomerization, a transmembrane domain, and a short cytoplasmic domain required for organelle targeting. Allelic variants of this gene are associated with the autosomal recessive disorder combined factor V-factor VIII deficiency.,LMAN1,ERGIC-53,ERGIC53,F5F8D,FMFD1,MCFD1,MR60,gp58,Signal Transduction,LMAN1
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Molekulargewicht
- 57 kDa
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Gen-ID
- 3998
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UniProt
- P49257
Target
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