CBR1 Antikörper

Produktnummer ABIN614308

Dieses Maus Monoklonal-Antikörper erkennt spezifisch CBR1 in WB und EIA. Er zeigt eine Reaktivität gegenüber Human.

Kurzübersicht für CBR1 Antikörper (ABIN614308)

Target: CBR1 (Carbonyl Reductase 1 (CBR1))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser CBR1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Enzyme Immunoassay (EIA)

Klon: AT4E12

Produktdetails anti-CBR1 Antikörper

Spezifität: The antibody recognizes human CBR1. Other species not tested.

Aufreinigung: Protein-G affinity chromatography

Isotyp: IgG2a

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1.0 mg/mL

Buffer: PBS, pH 7.4, containing 0.09 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Details zu CBR1

Target: CBR1 (Carbonyl Reductase 1 (CBR1))

Andere Bezeichnung: Carbonyl Reductase 1

Hintergrund: Carbonyl reductase 1 (CBR1) is a NADPH-dependent, monomeric, and cytosolic enzyme belonging to a family of short-chain dehydrogenases/reductases. This protein consists of 277 amino acid residues and is widely distributed in human tissues such as liver, epidermis, stomach, small intestine, kidney, neuronal cells, and smooth muscle fiber. CBR1 metabolizes many toxic environmental quinones and pharmacological relevant substrates such as the anticancer drug, doxorubicin. The best substrates of CBR1 are quinones, including ubiquinone-1 and tocophrolquinone (vitamin E).Synonyms: 15-hydroxyprostaglandin dehydrogenase [NADP+], CBR, CBR1, CRN, NADPH-dependent carbonyl reductase 1, Prostaglandin 9-ketoreductase, Prostaglandin-E(2) 9-reductase

Gen-ID: 873