L1CAM Antikörper (AA 1143-1257)

Produktnummer ABIN6143053

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch L1CAM in WB und IF. Er zeigt eine Reaktivität gegenüber Human.

Kurzübersicht für L1CAM Antikörper (AA 1143-1257) (ABIN6143053)

Target: L1CAM (L1 Cell Adhesion Molecule (L1CAM))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser L1CAM Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (IF)

Produktdetails anti-L1CAM Antikörper

Bindungsspezifität: AA 1143-1257

Sequenz: IKRSKGGKYS VKDKEDTQVD SEARPMKDET FGEYRSLESD NEEKAFGSSQ PSLNGDIKPL GSDDSLADYG GSVDVQFNED GSFIGQYSGK KEKEAAGGND SSGATSPINP AVALE

Kreuzreaktivität: Human, Maus, Ratte

Produktmerkmale: Polyclonal Antibodies

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1143-1257 of human L1CAM (NP_000416.1).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB,1:500 - 1:2000,IF,1:50 - 1:200

Kommentare:

HIGH QUALITY

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu L1CAM

Target: L1CAM (L1 Cell Adhesion Molecule (L1CAM))

Andere Bezeichnung: L1CAM

Hintergrund: The protein encoded by this gene is an axonal glycoprotein belonging to the immunoglobulin supergene family. The ectodomain, consisting of several immunoglobulin-like domains and fibronectin-like repeats (type III), is linked via a single transmembrane sequence to a conserved cytoplasmic domain. This cell adhesion molecule plays an important role in nervous system development, including neuronal migration and differentiation. Mutations in the gene cause X-linked neurological syndromes known as CRASH (corpus callosum hypoplasia, retardation, aphasia, spastic paraplegia and hydrocephalus). Alternative splicing of this gene results in multiple transcript variants, some of which include an alternate exon that is considered to be specific to neurons.,L1CAM,CAML1,CD171,HSAS,HSAS1,MASA,MIC5,N-CAM-L1,N-CAML1,NCAM-L1,S10,SPG1,Signal Transduction,Cell Biology & Developmental Biology,Cell Adhesion,Cell Adhesion Molecules,Cytoskeleton,Immunology & Inflammation,CD markers,Neuroscience,Amyloid Plaque and Neurofibrillary Tangle Formation in Alzheimer's Disease,Neurodegenerative Diseases Markers,L1CAM

Molekulargewicht: 138 kDa/139 kDa/140 kDa

Gen-ID: 3897

UniProt: P32004

Pathways: Synaptic Membrane