KRT81 Antikörper (AA 240-390)

Produktnummer ABIN6143041

Produktdetails anti-KRT81 Antikörper

Target: KRT81 (Keratin 81 (KRT81))

Bindungsspezifität: AA 240-390

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser KRT81 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: RRLYEEEILI LQSHISDTSV VVKLDNSRDL NMDCIIAEIK AQYDDIVTRS RAEAESWYRS KCEEMKATVI RHGETLRRTK EEINELNRMI QRLTAEVENA KCQNSKLEAA VAQSEQQGEA ALSDARCKLA ELEGALQKAK QDMACLIREY Q

Kreuzreaktivität: Human, Maus

Produktmerkmale: Polyclonal Antibodies

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 240-390 of human KRT81 (NP_002272.2).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB,1:500 - 1:2000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu KRT81

Target: KRT81 (Keratin 81 (KRT81))

Andere Bezeichnung: KRT81 (KRT81 Produkte)

Hintergrund: The protein encoded by this gene is a member of the keratin gene family. As a type II hair keratin, it is a basic protein which heterodimerizes with type I keratins to form hair and nails. The type II hair keratins are clustered in a region of chromosome 12q13 and are grouped into two distinct subfamilies based on structure similarity. One subfamily, consisting of KRTHB1, KRTHB3, and KRTHB6, is highly related. The other less-related subfamily includes KRTHB2, KRTHB4, and KRTHB5. All hair keratins are expressed in the hair follicle, this hair keratin, as well as KRTHB3 and KRTHB6, is found primarily in the hair cortex. Mutations in this gene and KRTHB6 have been observed in patients with a rare dominant hair disease, monilethrix.,KRT81,HB1,Hb-1,KRTHB1,MLN137,ghHkb1,hHAKB2-1,Signal Transduction,Cell Biology & Developmental Biology,Cytoskeleton,Intermediate Filaments,Extracellular Matrix,Keratin,KRT81

Molekulargewicht: 54 kDa

Gen-ID: 3887

UniProt: Q14533