KIF14 Antikörper (AA 1399-1648)

Produktnummer ABIN6142854

Der Kaninchen Polyklonal Anti-KIF14-Antikörper wurde für WB, IHC und IF validiert. Er ist geeignet, KIF14 in Proben von Human zu detektieren.

Kurzübersicht für KIF14 Antikörper (AA 1399-1648) (ABIN6142854)

Target: KIF14 (Kinesin Family Member 14 (KIF14))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser KIF14 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Produktdetails anti-KIF14 Antikörper

Bindungsspezifität: AA 1399-1648

Sequenz: LENGNNKAAS VQEEFMDAVC DGVGLGMKIL LDSGLEKAKE LQHELFRQCT KNEVTKEMKT NAMGLIRSLE NIFAESKIKS FRRQVQEENF EYQDFKRMVN RAPEFLKLKH CLEKAIEIII SALKGCHSDI NLLQTCVESI RNLASDFYSD FSVPSTSVGS YESRVTHIVH QELESLAKSL LFCFESEESP DLLKPWETYN QNTKEEHQQS KSSGIDGSKN KGVPKRVYEL HGSSPAVSSE ECTPSRIQWV

Kreuzreaktivität: Human, Maus, Ratte

Produktmerkmale: Polyclonal Antibodies

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1399-1648 of human KIF14 (NP_055690.1).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB,1:1000 - 1:2000,IHC,1:50 - 1:200,IF,1:50 - 1:200

Kommentare:

HIGH QUALITY

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu KIF14

Target: KIF14 (Kinesin Family Member 14 (KIF14))

Andere Bezeichnung: KIF14

Hintergrund: This gene encodes a member of the kinesin-3 superfamily of microtubule motor proteins. These proteins are involved in numerous processes including vesicle transport, chromosome segregation, mitotic spindle formation, and cytokinesis. In human HeLa-S3 and 293T cells, this protein is localized to the cytoplasm during interphase, to the spindle poles and spindle microtubules during mitosis, and to the midbody during cytokinesis. An internal motor domain displays microtubule-dependent ATPase activity, consistent with its function as a microtubule motor protein. Knockdown of this gene results in failed cytokinesis with endoreplication, which results in multinucleated cells. This gene has been identified as a likely oncogene in breast, lung and ovarian cancers, as well as retinoblastomas and gliomas. Alternative splicing results in multiple transcript variants.,KIF14,MKS12,Signal Transduction,Cell Biology & Developmental Biology,Cytoskeleton,Microtubules,Motor Proteins,KIF14

Molekulargewicht: 186 kDa

Gen-ID: 9928

UniProt: Q15058