JTB Antikörper (AA 31-105)
Kurzübersicht für JTB Antikörper (AA 31-105) (ABIN6142668)
Target
Alle JTB Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 31-105
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Sequenz
- EAPVQEEKLS ASTSNLPCWL VEEFVVAEEC SPCSNFRAKT TPECGPTGYV EKITCSSSKR NEFKSCRSAL MEQRL
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Kreuzreaktivität
- Human, Ratte
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Produktmerkmale
- Polyclonal Antibodies
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Immunogen
- Recombinant fusion protein containing a sequence corresponding to amino acids 31-105 of human JTB (NP_006685.1).
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Isotyp
- IgG
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Applikationshinweise
- WB,1:500 - 1:2000
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Kommentare
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HIGH QUALITY
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Store at -20°C. Avoid freeze / thaw cycles.
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- JTB (Jumping Translocation Breakpoint (JTB))
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Andere Bezeichnung
- JTB
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Hintergrund
- Required for normal cytokinesis during mitosis. Plays a role in the regulation of cell proliferation. May be a component of the chromosomal passenger complex (CPC, a complex that acts as a key regulator of mitosis. The CPC complex has essential functions at the centromere in ensuring correct chromosome alignment and segregation and is required for chromatin-induced microtubule stabilization and spindle assembly. Increases AURKB activity. Inhibits apoptosis induced by TGFB1 (By similarity. Overexpression induces swelling of mitochondria and reduces mitochondrial membrane potential (By similarity.,JTB,HJTB,HSPC222,PAR,hJT,Cell Biology & Developmental Biology,JTB
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Molekulargewicht
- 13 kDa/16 kDa
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Gen-ID
- 10899
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UniProt
- O76095
Target
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