JARID2 Antikörper (AA 1027-1246)
Kurzübersicht für JARID2 Antikörper (AA 1027-1246) (ABIN6142653)
Target
Alle JARID2 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 1027-1246
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Sequenz
- ETVHFATTQW TSMGFETAKE MKRRHIAKPF SMEKLLYQIA QAEAKKENGP TLSTISALLD ELRDTELRQR RQLFEAGLHS SARYGSHDGS STVADGKKKP RKWLQLETSE RRCQICQHLC YLSMVVQENE NVVFCLECAL RHVEKQKSCR GLKLMYRYDE EQIISLVNQI CGKVSGKNGS IENCLSKPTP KRGPRKRATV DVPPSRLSAS SSSKSASSSS
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Kreuzreaktivität
- Human, Maus, Ratte
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Produktmerkmale
- Polyclonal Antibodies
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Immunogen
- Recombinant fusion protein containing a sequence corresponding to amino acids 1027-1246 of human JARID2 (NP_004964.2).
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Isotyp
- IgG
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Applikationshinweise
- WB,1:500 - 1:2000
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Kommentare
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HIGH QUALITY
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Store at -20°C. Avoid freeze / thaw cycles.
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- JARID2 (Jumonji, AT Rich Interactive Domain 2 (JARID2))
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Andere Bezeichnung
- JARID2
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Hintergrund
- This gene encodes a Jumonji- and AT-rich interaction domain (ARID)-domain-containing protein. The encoded protein is a DNA-binding protein that functions as a transcriptional repressor. This protein interacts with the Polycomb repressive complex 2 (PRC2) which plays an essential role in regulating gene expression during embryonic development. This protein facilitates the recruitment of the PRC2 complex to target genes. Alternate splicing results in multiple transcript variants. Mutations in this gene are associated with chronic myeloid malignancies.,JARID2,JMJ,Epigenetics & Nuclear Signaling,Neuroscience,JARID2
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Molekulargewicht
- 106 kDa/119 kDa/138 kDa
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Gen-ID
- 3720
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UniProt
- Q92833
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Pathways
- Chromatin Binding
Target
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