ITGA8 Antikörper (AA 907-1000)

Produktnummer ABIN6142568

Der Kaninchen Polyklonal Anti-ITGA8-Antikörper wurde für WB validiert. Er ist geeignet, ITGA8 in Proben von Human zu detektieren.

Kurzübersicht für ITGA8 Antikörper (AA 907-1000) (ABIN6142568)

Target: ITGA8 (Integrin alpha-8 (ITGA8))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ITGA8 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-ITGA8 Antikörper

Bindungsspezifität: AA 907-1000

Sequenz: DVHVVEFHRQ SPAKILNCTN IECLQISCAV GRLEGGESAV LKVRSRLWAH TFLQRKNDPY ALASLVSFEV KKMPYTDQPA KLPEGSIVIK TSVI

Kreuzreaktivität: Human, Maus, Ratte

Produktmerkmale: Polyclonal Antibodies

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 907-1000 of human ITGA8 (NP_003629.2).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB,1:500 - 1:2000

Kommentare:

HIGH QUALITY

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu ITGA8

Target: ITGA8 (Integrin alpha-8 (ITGA8))

Andere Bezeichnung: ITGA8

Hintergrund: Integrins are heterodimeric transmembrane receptor proteins that mediate numerous cellular processes including cell adhesion, cytoskeletal rearrangement, and activation of cell signaling pathways. Integrins are composed of alpha and beta subunits. This gene encodes the alpha 8 subunit of the heterodimeric integrin alpha8beta1 protein. The encoded protein is a single-pass type 1 membrane protein that contains multiple FG-GAP repeats. This repeat is predicted to fold into a beta propeller structure. This gene regulates the recruitment of mesenchymal cells into epithelial structures, mediates cell-cell interactions, and regulates neurite outgrowth of sensory and motor neurons. The integrin alpha8beta1 protein thus plays an important role in wound-healing and organogenesis. Mutations in this gene have been associated with renal hypodysplasia/aplasia-1 (RHDA1) and with several animal models of chronic kidney disease. Alternate splicing results in multiple transcript variants encoding distinct isoforms.,ITGA8,Signal Transduction,PI3K-Akt Signaling Pathway,MAPK-Erk Signaling Pathway,Cell Biology & Developmental Biology,Cell Adhesion,Cytoskeleton,ITGA8

Molekulargewicht: 117 kDa

Gen-ID: 8516

UniProt: P53708