ITGA6 Antikörper (AA 870-1010)
Kurzübersicht für ITGA6 Antikörper (AA 870-1010) (ABIN6142566)
Target
Alle ITGA6 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 870-1010
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Sequenz
- KVESKGLEKV TCEPQKEINS LNLTESHNSR KKREITEKQI DDNRKFSLFA ERKYQTLNCS VNVNCVNIRC PLRGLDSKAS LILRSRLWNS TFLEEYSKLN YLDILMRAFI DVTAAAENIR LPNAGTQVRV TVFPSKTVAQ Y
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Kreuzreaktivität
- Human, Maus, Ratte
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Produktmerkmale
- Polyclonal Antibodies
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Immunogen
- Recombinant fusion protein containing a sequence corresponding to amino acids 870-1010 of human Integrin alpha 6 (ITGA6/CD49f) (NP_001073286.1).
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Isotyp
- IgG
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Applikationshinweise
- WB,1:500 - 1:2000
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Kommentare
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HIGH QUALITY
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Store at -20°C. Avoid freeze / thaw cycles.
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- ITGA6 (Integrin, alpha 6 (ITGA6))
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Andere Bezeichnung
- ITGA6
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Hintergrund
- The gene encodes a member of the integrin alpha chain family of proteins. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain that function in cell surface adhesion and signaling. The encoded preproprotein is proteolytically processed to generate light and heavy chains that comprise the alpha 6 subunit. This subunit may associate with a beta 1 or beta 4 subunit to form an integrin that interacts with extracellular matrix proteins including members of the laminin family. The alpha 6 beta 4 integrin may promote tumorigenesis, while the alpha 6 beta 1 integrin may negatively regulate erbB2/HER2 signaling. Alternative splicing results in multiple transcript variants.,CD49f,ITGA6B,VLA-6,Integrin alpha 6,ITGA6,Signal Transduction,G protein signaling,G2/M DNA Damage Checkpoint,PI3K-Akt Signaling Pathway,MAPK-Erk Signaling Pathway,Cell Biology & Developmental Biology,Cell Adhesion,Cytoskeleton,Immunology & Inflammation,CD markers,Stem Cells,Embryonic Stem Cells,Hematopoietic Progenitors,ITGA6
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Molekulargewicht
- 106 kDa/119 kDa/121 kDa/122 kDa/124 kDa/126 kDa
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Gen-ID
- 3655
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UniProt
- P23229
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Pathways
- CXCR4-mediated Signaling Events, Brown Fat Cell Differentiation, Integrin Complex
Target
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