ITGA5 Antikörper (AA 750-1000)
Kurzübersicht für ITGA5 Antikörper (AA 750-1000) (ABIN6142564)
Target
Alle ITGA5 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 750-1000
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Sequenz
- TVPHLRDTKK TIQFDFQILS KNLNNSQSDV VSFRLSVEAQ AQVTLNGVSK PEAVLFPVSD WHPRDQPQKE EDLGPAVHHV YELINQGPSS ISQGVLELSC PQALEGQQLL YVTRVTGLNC TTNHPINPKG LELDPEGSLH HQQKREAPSR SSASSGPQIL KCPEAECFRL RCELGPLHQQ ESQSLQLHFR VWAKTFLQRE HQPFSLQCEA VYKALKMPYR ILPRQLPQKE RQVATAVQWT KAEGSYGVPL W
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Kreuzreaktivität
- Human, Maus, Ratte
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Produktmerkmale
- Polyclonal Antibodies
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Immunogen
- Recombinant fusion protein containing a sequence corresponding to amino acids 750-1000 of human Integrin alpha 5 (ITGA5/CD49e) (NP_002196.4).
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Isotyp
- IgG
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Applikationshinweise
- WB,1:500 - 1:2000,IF,1:50 - 1:200
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Kommentare
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HIGH QUALITY
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Store at -20°C. Avoid freeze / thaw cycles.
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- ITGA5 (Integrin, alpha 5 (ITGA5))
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Andere Bezeichnung
- ITGA5
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Hintergrund
- The product of this gene belongs to the integrin alpha chain family. Integrins are heterodimeric integral membrane proteins composed of an alpha subunit and a beta subunit that function in cell surface adhesion and signaling. The encoded preproprotein is proteolytically processed to generate light and heavy chains that comprise the alpha 5 subunit. This subunit associates with the beta 1 subunit to form a fibronectin receptor. This integrin may promote tumor invasion, and higher expression of this gene may be correlated with shorter survival time in lung cancer patients. Note that the integrin alpha 5 and integrin alpha V subunits are encoded by distinct genes.,CD49e,FNRA,VLA-5,VLA5A,Integrin alpha 5,ITGA5,Signal Transduction,G protein signaling,G2/M DNA Damage Checkpoint,PI3K-Akt Signaling Pathway,MAPK-Erk Signaling Pathway,Cell Biology & Developmental Biology,Cell Adhesion,Cytoskeleton,Immunology & Inflammation,CD markers,Stem Cells,Endothelial Progenitors,Hematopoietic Progenitors,ITGA5
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Molekulargewicht
- 114 kDa
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Gen-ID
- 3678
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UniProt
- P08648
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Pathways
- Integrin Complex
Target
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