ISY1
Reaktivität: Human
WB
Wirt: Kaninchen
Polyclonal
unconjugated
Applikationshinweise
WB,1:500 - 1:2000
Beschränkungen
Nur für Forschungszwecke einsetzbar
Format
Liquid
Buffer
PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
Konservierungsmittel
Sodium azide
Vorsichtsmaßnahmen
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung
-20 °C
Informationen zur Lagerung
Store at -20°C. Avoid freeze / thaw cycles.
Target
ISY1
(ISY1 Splicing Factor Homolog (ISY1))
Andere Bezeichnung
ISY1
Hintergrund
Component of the spliceosome C complex required for the selective processing of microRNAs during embryonic stem cell differentiation (By similarity. Required for the biogenesis of all miRNAs from the pri-miR-17-92 primary transcript except miR-92a (By similarity. Only required for the biogenesis of miR-290 and miR-96 from the pri-miR-290-295 and pri-miR-96-183 primary transcripts, respectively (By similarity. Required during the transition of embryonic stem cells (ESCs from the naive to primed state (By similarity. By enhancing miRNA biogenesis, promotes exit of ESCs from the naive state to an intermediate state of poised pluripotency, which precedes transition to the primed state (By similarity. Involved in pre-mRNA splicing as component of the spliceosome.,ISY1,FSAP33,Epigenetics & Nuclear Signaling,RNA Binding,ISY1