IRS2 Antikörper (AA 510-650)

Produktnummer ABIN6142544

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch IRS2 in WB und IF. Er zeigt eine Reaktivität gegenüber Human.

Kurzübersicht für IRS2 Antikörper (AA 510-650) (ABIN6142544)

Target: IRS2 (Insulin Receptor Substrate 2 (IRS2))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser IRS2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (IF)

Produktdetails anti-IRS2 Antikörper

Bindungsspezifität: AA 510-650

Sequenz: LRAFCSHRSN TPESIAETPP ARDGGGGGEF YGYMTMDRPL SHCGRSYRRV SGDAAQDLDR GLRKRTYSLT TPARQRPVPQ PSSASLDEYT LMRATFSGSA GRLCPSCPAS SPKVAYHPYP EDYGDIEIGS HRSSSSNLGA D

Kreuzreaktivität: Human, Maus, Ratte

Produktmerkmale: Polyclonal Antibodies

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 510-650 of human IRS2 (NP_003740.2).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB,1:500 - 1:2000,IF,1:50 - 1:200

Kommentare:

HIGH QUALITY

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu IRS2

Target: IRS2 (Insulin Receptor Substrate 2 (IRS2))

Andere Bezeichnung: IRS2

Hintergrund: This gene encodes the insulin receptor substrate 2, a cytoplasmic signaling molecule that mediates effects of insulin, insulin-like growth factor 1, and other cytokines by acting as a molecular adaptor between diverse receptor tyrosine kinases and downstream effectors. The product of this gene is phosphorylated by the insulin receptor tyrosine kinase upon receptor stimulation, as well as by an interleukin 4 receptor-associated kinase in response to IL4 treatment.,IRS2,IRS-2,Cancer,Signal Transduction,MAPK-Erk Signaling Pathway,Cell Biology & Developmental Biology,Growth factor,Endocrine & Metabolism,Insulin Receptor Signaling Pathway,Endocrine and metabolic diseases,Diabetes,Immunology & Inflammation,Cardiovascular,Heart,Cardiovascular diseases,Heart disease,IRS2

Molekulargewicht: 137 kDa

Gen-ID: 8660

UniProt: Q9Y4H2

Pathways: Fc-epsilon Rezeptor Signalübertragung, EGFR Signaling Pathway, Neurotrophin Signalübertragung, Positive Regulation of Peptide Hormone Secretion, Response to Growth Hormone Stimulus, Carbohydrate Homeostasis, Regulation of Carbohydrate Metabolic Process