IRF8 Antikörper (AA 137-426)

Produktnummer ABIN6142538

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch IRF8 in WB. Er zeigt eine Reaktivität gegenüber Human und wurde in 1 Publikation erwähnt.

Kurzübersicht für IRF8 Antikörper (AA 137-426) (ABIN6142538)

Target: IRF8 (Interferon Regulatory Factor 8 (IRF8))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser IRF8 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-IRF8 Antikörper

Bindungsspezifität: AA 137-426

Sequenz: ECGRSEIDEL IKEPSVDDYM GMIKRSPSPP EACRSQLLPD WWAQQPSTGV PLVTGYTTYD AHHSAFSQMV ISFYYGGKLV GQATTTCPEG CRLSLSQPGL PGTKLYGPEG LELVRFPPAD AIPSERQRQV TRKLFGHLER GVLLHSSRQG VFVKRLCQGR VFCSGNAVVC KGRPNKLERD EVVQVFDTSQ FFRELQQFYN SQGRLPDGRV VLCFGEEFPD MAPLRSKLIL VQIEQLYVRQ LAEEAGKSCG AGSVMQAPEE PPPDQVFRMF PDICASHQRS FFRENQQITV

Kreuzreaktivität: Human, Maus

Produktmerkmale: Polyclonal Antibodies

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 137-426 of human IRF8 (NP_002154.1).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB,1:500 - 1:2000

Kommentare:

HIGH QUALITY

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Referenzen für anti-IRF8 Antikörper (ABIN6142538)

Yu, Liu, Zhu, Zhu, Lv, Wang, Wang, Peng: "The Expression of Interferon Regulatory Factor 8 in Human Periapical Lesions." in: Journal of endodontics, Vol. 44, Issue 8, pp. 1276-1282, (2019) (PubMed).

Details zu IRF8

Target: IRF8 (Interferon Regulatory Factor 8 (IRF8))

Andere Bezeichnung: IRF8

Hintergrund: Interferon consensus sequence-binding protein (ICSBP) is a transcription factor of the interferon (IFN) regulatory factor (IRF) family. Proteins of this family are composed of a conserved DNA-binding domain in the N-terminal region and a divergent C-terminal region that serves as the regulatory domain. The IRF family proteins bind to the IFN-stimulated response element (ISRE) and regulate expression of genes stimulated by type I IFNs, namely IFN-alpha and IFN-beta. IRF family proteins also control expression of IFN-alpha and IFN-beta-regulated genes that are induced by viral infection.,IRF8,H-ICSBP,ICSBP,ICSBP1,IMD32A,IMD32B,IRF-8,Epigenetics & Nuclear Signaling,Transcription Factors,Immunology & Inflammation,Toll-like Receptor Signaling Pathway,Cell Intrinsic Innate Immunity Signaling Pathway,TLR Signaling,IRF8

Molekulargewicht: 48 kDa

Gen-ID: 3394

UniProt: Q02556

Pathways: Cellular Response to Molecule of Bacterial Origin