Der Kaninchen Polyklonal anti-IREB2 Antikörper (ABIN6142524) detektiert spezifisch IREB2 in WB und IF.
Dieser Antikörper reagiert spezifisch mit Proben aus Human.
IREB2
Reaktivität: Human
WB
Wirt: Maus
Polyclonal
unconjugated
Applikationshinweise
WB,1:500 - 1:2000,IF,1:20 - 1:50
Beschränkungen
Nur für Forschungszwecke einsetzbar
Format
Liquid
Buffer
PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
Konservierungsmittel
Sodium azide
Vorsichtsmaßnahmen
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung
-20 °C
Informationen zur Lagerung
Store at -20°C. Avoid freeze / thaw cycles.
Target
IREB2
(Iron-Responsive Element Binding Protein 2 (IREB2))
Andere Bezeichnung
IREB2
Hintergrund
RNA-binding protein that binds to iron-responsive elements (IRES, which are stem-loop structures found in the 5'-UTR of ferritin, and delta aminolevulinic acid synthase mRNAs, and in the 3'-UTR of transferrin receptor mRNA. Binding to the IRE element in ferritin results in the repression of its mRNA translation. Binding of the protein to the transferrin receptor mRNA inhibits the degradation of this otherwise rapidly degraded mRNA.,IREB2,ACO3,IRP2,IRP2AD,Endocrine & Metabolism,Cardiovascular,Hypoxia,Hypoxia-Regulated,IREB2