HDAC5 Antikörper (AA 550-650)

Produktnummer ABIN6141675

Der Kaninchen Polyklonal Anti-HDAC5-Antikörper wurde für WB, IHC und IF validiert. Er ist geeignet, HDAC5 in Proben von Human zu detektieren.

Kurzübersicht für HDAC5 Antikörper (AA 550-650) (ABIN6141675)

Target: HDAC5 (Histone Deacetylase 5 (HDAC5))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser HDAC5 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Produktdetails anti-HDAC5 Antikörper

Bindungsspezifität: AA 550-650

Sequenz: EETEEELTEQ QEVLLGEGAL TMPREGSTES ESTQEDLEEE DEEDDGEEEE DCIQVKDEEG ESGAEEGPDL EEPGAGYKKL FSDAQPLQPL QVYQAPLSLA T

Kreuzreaktivität: Human, Maus, Ratte

Produktmerkmale: Polyclonal Antibodies

Aufreinigung: Affinity purification

Immunogen: A synthetic peptide corresponding to a sequence within amino acids 550-650 of human HDAC5 (NP_005465.2).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB,1:500 - 1:2000,IHC,1:50 - 1:200,IF,1:50 - 1:200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu HDAC5

Target: HDAC5 (Histone Deacetylase 5 (HDAC5))

Andere Bezeichnung: HDAC5

Hintergrund: Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to the class II histone deacetylase/acuc/apha family. It possesses histone deacetylase activity and represses transcription when tethered to a promoter. It coimmunoprecipitates only with HDAC3 family member and might form multicomplex proteins. It also interacts with myocyte enhancer factor-2 (MEF2) proteins, resulting in repression of MEF2-dependent genes. This gene is thought to be associated with colon cancer. Two transcript variants encoding different isoforms have been found for this gene.,HDAC5,HD5,NY-CO-9,Epigenetics & Nuclear Signaling,Nuclear Receptor Signaling,Signal Transduction,Cell Biology & Developmental Biology,Cell Cycle,G1/S Checkpoint,Notch Signaling Pathway,Wnt/β-Catenin Signaling Pathway,Immunology & Inflammation,NF-kB Signaling Pathway,Stem Cells,Cardiovascular,Heart,Hypertrophy,HDAC5

Molekulargewicht: 112 kDa/121 kDa/122 kDa

Gen-ID: 10014

UniProt: Q9UQL6

Pathways: Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development, Monocarboxylic Acid Catabolic Process