Glutathione Reductase Antikörper (AA 273-522)
Kurzübersicht für Glutathione Reductase Antikörper (AA 273-522) (ABIN6141458)
Target
Alle Glutathione Reductase (GSR) Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 273-522
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Sequenz
- MISTNCTEEL ENAGVEVLKF SQVKEVKKTL SGLEVSMVTA VPGRLPVMTM IPDVDCLLWA IGRVPNTKDL SLNKLGIQTD DKGHIIVDEF QNTNVKGIYA VGDVCGKALL TPVAIAAGRK LAHRLFEYKE DSKLDYNNIP TVVFSHPPIG TVGLTEDEAI HKYGIENVKT YSTSFTPMYH AVTKRKTKCV MKMVCANKEE KVVGIHMQGL GCDEMLQGFA VAVKMGATKA DFDNTVAIHP TSSEELVTLR
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Kreuzreaktivität
- Human, Maus
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Produktmerkmale
- Polyclonal Antibodies
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Aufreinigung
- Affinity purification
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Immunogen
- Recombinant fusion protein containing a sequence corresponding to amino acids 273-522 of human GSR (NP_000628.2).
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Isotyp
- IgG
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Applikationshinweise
- WB,1:500 - 1:2000
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Kommentare
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HIGH QUALITY
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Store at -20°C. Avoid freeze / thaw cycles.
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- Glutathione Reductase (GSR)
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Andere Bezeichnung
- GSR
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Hintergrund
- This gene encodes a member of the class-I pyridine nucleotide-disulfide oxidoreductase family. This enzyme is a homodimeric flavoprotein. It is a central enzyme of cellular antioxidant defense, and reduces oxidized glutathione disulfide (GSSG) to the sulfhydryl form GSH, which is an important cellular antioxidant. Rare mutations in this gene result in hereditary glutathione reductase deficiency. Multiple alternatively spliced transcript variants encoding different isoforms have been found.,GSR,HEL-75,HEL-S-122m,Cancer,Signal Transduction,Cell Biology & Developmental Biology,Endocrine & Metabolism,Mitochondrial metabolism,Mitochondrial markers,GSR
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Molekulargewicht
- 47 kDa/50 kDa/51 kDa/53 kDa/56 kDa
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Gen-ID
- 2936
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UniProt
- P00390
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Pathways
- Thyroid Hormone Synthesis, Cell RedoxHomeostasis
Target
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