Gephyrin Antikörper (AA 520-769)
Kurzübersicht für Gephyrin Antikörper (AA 520-769) (ABIN6141324)
Target
Alle Gephyrin (GPHN) Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 520-769
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Sequenz
- TVGVTEVEVN KFPVVAVMST GNELLNPEDD LLPGKIRDSN RSTLLATIQE HGYPTINLGI VGDNPDDLLN ALNEGISRAD VIITSGGVSM GEKDYLKQVL DIDLHAQIHF GRVFMKPGLP TTFATLDIDG VRKIIFALPG NPVSAVVTCN LFVVPALRKM QGILDPRPTI IKARLSCDVK LDPRPEYHRC ILTWHHQEPL PWAQSTGNQM SSRLMSMRSA NGLLMLPPKT EQYVELHKGE VVDVMVIGRL
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Kreuzreaktivität
- Human, Maus, Ratte
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Produktmerkmale
- Polyclonal Antibodies
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Aufreinigung
- Affinity purification
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Immunogen
- Recombinant fusion protein containing a sequence corresponding to amino acids 520-769 of human Gephyrin (NP_065857.1).
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Isotyp
- IgG
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Applikationshinweise
- WB,1:500 - 1:2000
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Kommentare
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HIGH QUALITY
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Store at -20°C. Avoid freeze / thaw cycles.
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- Gephyrin (GPHN)
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Andere Bezeichnung
- GPHN
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Hintergrund
- This gene encodes a neuronal assembly protein that anchors inhibitory neurotransmitter receptors to the postsynaptic cytoskeleton via high affinity binding to a receptor subunit domain and tubulin dimers. In nonneuronal tissues, the encoded protein is also required for molybdenum cofactor biosynthesis. Mutations in this gene may be associated with the neurological condition hyperplexia and also lead to molybdenum cofactor deficiency. Numerous alternatively spliced transcript variants encoding different isoforms have been described, however, the full-length nature of all transcript variants is not currently known.,GPHN,GEPH,GPH,GPHRYN,HKPX1,MOCODC,gephyrin,Cell Biology & Developmental Biology,Cell Adhesion,Microtubules,Neuroscience,GPHN
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Molekulargewicht
- 79 kDa/83 kDa
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Gen-ID
- 10243
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UniProt
- Q9NQX3
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Pathways
- Synaptic Membrane, Skeletal Muscle Fiber Development
Target
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