GGCX Antikörper (AA 479-758)
Kurzübersicht für GGCX Antikörper (AA 479-758) (ABIN6141069)
Target
Alle GGCX Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 479-758
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Sequenz
- QRIFDPRVDI VQAAWSPFQR TSWVQPLLMD LSPWRAKLQE IKSSLDNHTE VVFIADFPGL HLENFVSEDL GNTSIQLLQG EVTVELVAEQ KNQTLREGEK MQLPAGEYHK VYTTSPSPSC YMYVYVNTTE LALEQDLAYL QELKEKVENG SETGPLPPEL QPLLEGEVKG GPEPTPLVQT FLRRQQRLQE IERRRNTPFH ERFFRFLLRK LYVFRRSFLM TCISLRNLIL GRPSLEQLAQ EVTYANLRPF EAVGELNPSN TDSSHSNPPE SNPDPVHSEF
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Kreuzreaktivität
- Human, Maus
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Produktmerkmale
- Polyclonal Antibodies
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Aufreinigung
- Affinity purification
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Immunogen
- Recombinant fusion protein containing a sequence corresponding to amino acids 479-758 of human GGCX (NP_000812.2).
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Isotyp
- IgG
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Applikationshinweise
- WB,1:500 - 1:2000
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Kommentare
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HIGH QUALITY
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Store at -20°C. Avoid freeze / thaw cycles.
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- GGCX (gamma-Glutamyl Carboxylase (GGCX))
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Andere Bezeichnung
- GGCX
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Hintergrund
- This gene encodes an integral membrane protein of the rough endoplasmic reticulum that carboxylates glutamate residues of vitamin K-dependent proteins to gamma carboxyl glutamate, a modification that is required for their activity. The vitamin K-dependent protein substrates have a propeptide that binds the enzyme, with carbon dioxide, dioxide, and reduced vitamin K acting as co-substrates. Vitamin K-dependent proteins affect a number of physiologic processes including blood coagulation, prevention of vascular calcification, and inflammation. Allelic variants of this gene have been associated with pseudoxanthoma elasticum-like disorder with associated multiple coagulation factor deficiency. Alternative splicing results in multiple transcript variants.,GGCX,VKCFD1,Cardiovascular,Blood,Coagulation,GGCX
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Molekulargewicht
- 80 kDa/87 kDa
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Gen-ID
- 2677
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UniProt
- P38435
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Pathways
- SARS-CoV-2 Protein Interaktom
Target
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