GDF5 Antikörper (AA 350-450)

Produktnummer ABIN6141044

Dieses Anti-GDF5-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von GDF5 in WB und IHC. Geeignet für Human.

Kurzübersicht für GDF5 Antikörper (AA 350-450) (ABIN6141044)

Target: GDF5 (Growth Differentiation Factor 5 (GDF5))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser GDF5 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Produktdetails anti-GDF5 Antikörper

Bindungsspezifität: AA 350-450

Sequenz: KRDLFFNEIK ARSGQDDKTV YEYLFSQRRK RRAPLATRQG KRPSKNLKAR CSRKALHVNF KDMGWDDWII APLEYEAFHC EGLCEFPLRS HLEPTNHAVI Q

Kreuzreaktivität: Maus, Ratte

Produktmerkmale: Polyclonal Antibodies

Aufreinigung: Affinity purification

Immunogen: A synthetic peptide corresponding to a sequence within amino acids 350-450 of human GDF5 (NP_000548.2).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB,1:500 - 1:2000,IHC,1:50 - 1:200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu GDF5

Target: GDF5 (Growth Differentiation Factor 5 (GDF5))

Andere Bezeichnung: GDF5

Hintergrund: This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer. This protein regulates the development of numerous tissue and cell types, including cartilage, joints, brown fat, teeth, and the growth of neuronal axons and dendrites. Mutations in this gene are associated with acromesomelic dysplasia, brachydactyly, chondrodysplasia, multiple synostoses syndrome, proximal symphalangism, and susceptibility to osteoarthritis.,GDF5,BDA1C,BMP-14,BMP14,CDMP1,LAP-4,LAP4,OS5,SYM1B,SYNS2,Signal Transduction,Cell Biology & Developmental Biology,Apoptosis,Growth factor,Immunology & Inflammation,Cytokines,Stem Cells,Cardiovascular,Angiogenesis,GDF5

Molekulargewicht: 55 kDa

Gen-ID: 8200

UniProt: P43026