GCDH Antikörper (AA 149-438)

Produktnummer ABIN6141009

Der Kaninchen Polyklonal Anti-GCDH-Antikörper wurde für WB validiert. Er ist geeignet, GCDH in Proben von Human zu detektieren.

Kurzübersicht für GCDH Antikörper (AA 149-438) (ABIN6141009)

Target: GCDH (Glutaryl-CoA Dehydrogenase (GCDH))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser GCDH Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-GCDH Antikörper

Bindungsspezifität: AA 149-438

Sequenz: MHPIYAYGSE EQRQKYLPQL AKGELLGCFG LTEPNSGSDP SSMETRAHYN SSNKSYTLNG TKTWITNSPM ADLFVVWARC EDGCIRGFLL EKGMRGLSAP RIQGKFSLRA SATGMIIMDG VEVPEENVLP GASSLGGPFG CLNNARYGIA WGVLGASEFC LHTARQYALD RMQFGVPLAR NQLIQKKLAD MLTEITLGLH ACLQLGRLKD QDKAAPEMVS LLKRNNCGKA LDIARQARDM LGGNGISDEY HVIRHAMNLE AVNTYEGTHD IHALILGRAI TGIQAFTASK

Kreuzreaktivität: Human, Maus, Ratte

Produktmerkmale: Polyclonal Antibodies

Aufreinigung: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 149-438 of human GCDH (NP_000150.1).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB,1:200 - 1:2000

Kommentare:

HIGH QUALITY

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu GCDH

Target: GCDH (Glutaryl-CoA Dehydrogenase (GCDH))

Andere Bezeichnung: GCDH

Hintergrund: The protein encoded by this gene belongs to the acyl-CoA dehydrogenase family. It catalyzes the oxidative decarboxylation of glutaryl-CoA to crotonyl-CoA and CO(2) in the degradative pathway of L-lysine, L-hydroxylysine, and L-tryptophan metabolism. It uses electron transfer flavoprotein as its electron acceptor. The enzyme exists in the mitochondrial matrix as a homotetramer of 45-kD subunits. Mutations in this gene result in the metabolic disorder glutaric aciduria type 1, which is also known as glutaric acidemia type I. Alternative splicing of this gene results in multiple transcript variants. A related pseudogene has been identified on chromosome 12.,GCDH,ACAD5,GCD,Cancer,Signal Transduction,Endocrine & Metabolism,Mitochondrial metabolism,Mitochondrial markers,Amino acid metabolism,GCDH

Molekulargewicht: 47 kDa/48 kDa

Gen-ID: 2639

UniProt: Q92947